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基于语音特征的阻塞性睡眠呼吸暂停严重程度评估

Severity evaluation of obstructive sleep apnea based on speech features.

作者信息

Ding Yiming, Wang Jiaxi, Gao Jiandong, Fang Qiang, Li Yanru, Xu Wen, Wu Ji, Han Demin

机构信息

Beijing Tongren Hospital, Capital Medical University, 1, Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, People's Republic of China.

Obstructive Sleep Apnea-Hypopnea Syndrome Clinical Diagnosis and Therapy and Research Centre, Capital Medical University, Beijing, 100730, People's Republic of China.

出版信息

Sleep Breath. 2021 Jun;25(2):787-795. doi: 10.1007/s11325-020-02168-0. Epub 2020 Oct 27.

Abstract

PURPOSE

There are upper airway abnormalities in patients with obstructive sleep apnea (OSA), and their speech signal characteristics are different from those of unaffected people. In this study, the severity of OSA was evaluated automatically by machine learning technology based on the speech signals of Chinese people.

METHODS

In total, 151 adult male Mandarin native speakers who had suspected OSA completed polysomnography to assess the severity of the disease. Chinese vowels and nasal sounds were recorded in sitting and supine positions, and the accuracy of predicting the apnea-hypopnea index (AHI) of the participants using a machine learning method was analyzed based on features extracted from the speech signals.

RESULTS

Among the 151 participants, 75 had AHI > 30 events/h, and 76 had AHI ≤ 30 events/h. Various features including linear prediction cepstral coefficients (LPCC) were extracted from the data collected from participants recorded in the sitting and supine positions and by using a linear support vector machine (SVM); we classified the participants with thresholds of AHI = 30 and AHI = 10 events/h. The accuracies of the classifications were both 78.8%, the sensitivities were 77.3% and 79.1%, and the specificities were 80.3% and 78.0%, respectively.

CONCLUSION

This study constructed a severity evaluation model of OSA based on speech signal processing and machine learning, which can be used as an effective method to screen patients with OSA. In addition, it was found that Chinese pronunciation can be used as an effective feature to predict OSA.

摘要

目的

阻塞性睡眠呼吸暂停(OSA)患者存在上呼吸道异常,其语音信号特征与未受影响的人不同。在本研究中,基于中国人的语音信号,通过机器学习技术自动评估OSA的严重程度。

方法

共有151名怀疑患有OSA的成年男性普通话母语者完成了多导睡眠图检查以评估疾病的严重程度。记录了他们在坐姿和仰卧位时的汉语元音和鼻音,并基于从语音信号中提取的特征,分析了使用机器学习方法预测参与者呼吸暂停低通气指数(AHI)的准确性。

结果

在151名参与者中,75人的AHI>30次/小时,76人的AHI≤30次/小时。从参与者在坐姿和仰卧位记录的数据中提取了包括线性预测倒谱系数(LPCC)在内的各种特征,并使用线性支持向量机(SVM);我们将参与者按AHI = 30次/小时和AHI = 10次/小时的阈值进行分类。分类的准确率均为78.8%,灵敏度分别为77.3%和79.1%,特异性分别为80.3%和78.0%。

结论

本研究构建了基于语音信号处理和机器学习技术的OSA严重程度评估模型,可作为筛查OSA患者的有效方法。此外,发现汉语发音可作为预测OSA的有效特征。

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