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2018 年波兰丙型肝炎流行情况。

Hepatitis C in Poland in 2018.

机构信息

National Institute of Public Health - National Institute of Hygiene in Warsaw, Department of Epidemiology of Infectious Diseases and Surveillance.

出版信息

Przegl Epidemiol. 2020;74(2):209-222. doi: 10.32394/pe.74.17.

Abstract

OBJECTIVE

Analysis of data on hepatitis C, collected as part of epidemiological surveillance in 2018, compared to previous years.

MATERIAL AND METHODS

Analysis of: 1) individual data from surveillance in 2018 2) diagnosis rate from bulletins "Infectious diseases and poisonings in Poland" for the years 2012-2018 and 3) data about deaths due to hepatitis C from the Demographic Surveys and Labour Market Department of the Central Statistical Office.

RESULTS

In 2018, there was a decrease in the number of reported hepatitis C cases (3,442 cases) and the diagnosis rate (8.96 per 100,000; taking into account the territorial distribution: from 3.29 per 100,000 in the Podkarpackie voivodeship to 13.69 per 100,00 in the Lubuskie voivodeship). The disproportion of the rates between the sexes returned (in men 9.34 per 100,000 vs. women: 8.61 per 100,000). The disproportion of the diagnosis rate depending on the place of residence was still evident (urban: 10.84 per 100,000 vs. rural: 6.12 per 100,000). There are differences in the values of the diagnosis rates, analyzed in terms of gender, age groups and the place of residence. Based on the EU definition, 14 acute hepatitis C were reported, while according to the PL definition, 88 cases (0.4% and 2.6% of all reported cases, respectively). HCV infections due to medical procedures are still the main route of transmission, also in cases of acute hepatitis C - which indicates the current route of transmission. According to the Demographic Surveys and Labour Market Department of the Central Statistical Office, 119 deaths related to hepatitis C were reported.

CONCLUSIONS

For years, the general picture of hepatitis C in Poland, observed through epidemiological surveillance, is determined by the availability of testing for HCV infections. The analysis identified subpopulations in which primary prevention activities (e.g. safer medical procedures, intensifying activities in the area of harm reduction for people who inject drugs) as well as secondary prevention (access to testing and quick inclusion in treatment) should be particularly strengthened. According to the micro-elimination strategy, the improvement of testing in particularly affected groups, including marginalized populations, is necessary to achieve the WHO goal of eliminating HCV by 2030.

摘要

目的

分析 2018 年作为流行病学监测一部分收集的丙型肝炎数据,与前几年进行比较。

材料与方法

分析:1)2018 年监测的个人数据,2)2012-2018 年“波兰传染病和中毒通报”的诊断率,以及 3)中央统计局人口调查和劳动力市场部门关于丙型肝炎死亡的数据。

结果

2018 年,丙型肝炎报告病例数(3442 例)和诊断率(每 10 万人 8.96 例;考虑到地域分布:从 10 万人 3.29 例的喀尔巴阡山省到 10 万人 13.69 例的卢布斯卡省)有所下降。性别间的比例失调有所恢复(男性每 10 万人 9.34 例,女性每 10 万人 8.61 例)。居住地对诊断率的影响仍然明显(城市每 10 万人 10.84 例,农村每 10 万人 6.12 例)。根据性别、年龄组和居住地分析,诊断率的值存在差异。根据欧盟的定义,报告了 14 例急性丙型肝炎,而根据波兰的定义,报告了 88 例(分别为所有报告病例的 0.4%和 2.6%)。医疗程序引起的 HCV 感染仍然是主要传播途径,即使是急性丙型肝炎也是如此——这表明了当前的传播途径。根据中央统计局人口调查和劳动力市场部门的数据,报告了 119 例与丙型肝炎相关的死亡。

结论

多年来,波兰通过流行病学监测观察到的丙型肝炎总体情况,取决于 HCV 感染检测的普及程度。分析确定了一些亚人群,应特别加强初级预防活动(例如更安全的医疗程序,加强针对注射毒品者的减少伤害领域的活动)和二级预防(检测和快速纳入治疗)。根据微消除战略,需要改善在受影响特别严重的群体(包括边缘化群体)中的检测,以实现世卫组织到 2030 年消除 HCV 的目标。

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