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孕前母体 BMI 预测新生儿出生体重。

Pre-pregnancy maternal BMI as predictor of neonatal birth weight.

机构信息

Department of Pediatrics, Fatima Memorial Hospital, Lahore, Shadman, Pakistan.

Department of Pediatrics, Combined Military Hospital, Lahore, Pakistan.

出版信息

PLoS One. 2020 Oct 28;15(10):e0240748. doi: 10.1371/journal.pone.0240748. eCollection 2020.

Abstract

INTRODUCTION

BMI is a tool to measure maternal nutritional status. Maternal malnutrition is frequently reported health problem especially during child bearing age and effects neonatal birth weight.

AIM

To determine relationship between prepregnancy maternal BMI and neonatal birth weight.

METHODS AND MATERIAL

Prospective, cross sectional study conducted in Fatima Memorial Hospital, Lahore, Pakistan over a period of 1 year including 2766 mother-neonate pairs. All full term, live born neonates of both gender in early neonatal period (<72 hours) with documented maternal pre-pregnancy and/or first trimester BMI were enrolled. Data analysis using SPSS version 20, was performed.

RESULTS

Data analysis of 2766 mother-neonates pairs showed that there were 32.9% overweight and 16.5% obese mothers. More than two third of all overweight and obese mothers were of age group between 26-35 years. Diabetes mellitus, hypertension, medical illness, uterine malformations and caesarean mode of delivery were more prevalent in obese mothers as 22.8%, 10.1%, 13.2%, 2.6% and 75.4% respectively. Mean birth weight, length and OFC increased with increasing maternal BMI. Comparing for normal weight mothers, underweight mothers were at increased risk of low birth weight (p< 0.01) and low risk of macrosomic neonates (p<0.01). However overweight and obese mothers were comparable to normal weight mothers for delivering macrosomic neonates (p 0.89 and p 0.66 respectively).

CONCLUSIONS

Our study highlights that direct relationship exists between maternal BMI and neonatal birth weight.

摘要

简介

BMI 是衡量产妇营养状况的工具。产妇营养不良是一个常见的健康问题,尤其是在生育年龄期间,会影响新生儿的出生体重。

目的

确定孕妇 BMI 与新生儿出生体重之间的关系。

方法和材料

这是一项在巴基斯坦拉合尔法蒂玛纪念医院进行的为期 1 年的前瞻性、横断面研究,共纳入了 2766 对母婴。所有足月、在新生儿早期(<72 小时)出生的活产新生儿,且记录有产妇孕前和/或孕早期 BMI,均纳入本研究。使用 SPSS 版本 20 进行数据分析。

结果

对 2766 对母婴的数据分析显示,有 32.9%的超重和 16.5%的肥胖母亲。超过三分之二的超重和肥胖母亲年龄在 26-35 岁之间。肥胖母亲中糖尿病、高血压、内科疾病、子宫畸形和剖宫产的发生率分别为 22.8%、10.1%、13.2%、2.6%和 75.4%。随着母亲 BMI 的增加,新生儿的平均出生体重、身长和头围增加。与正常体重母亲相比,体重不足的母亲发生低出生体重的风险增加(p<0.01),发生巨大儿的风险降低(p<0.01)。然而,超重和肥胖母亲与正常体重母亲相比,发生巨大儿的风险相似(p=0.89 和 p=0.66)。

结论

本研究表明,母亲 BMI 与新生儿出生体重之间存在直接关系。

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