Bancalari E, Goldberg R N
Department of Pediatrics, University of Miami School of Medicine, Florida.
Clin Perinatol. 1987 Sep;14(3):581-97.
HFV is a mode of therapy that allows gas exchange with pressure fluctuations much lower than that required for conventional ventilation, and may consequently decrease the incidence of barotrauma and chronic lung disease. At present the National Institute of Health is sponsoring the first large controlled trial to test the efficacy of HFV using an oscillator in premature infants with respiratory failure. Results of this trial will help to clarify some of the indications for HFV and its usefulness in a large number of infants with respiratory failure secondary to RDS.
高频通气是一种治疗方式，它能在压力波动比传统通气所需压力波动低得多的情况下实现气体交换，因此可能会降低气压伤和慢性肺病的发生率。目前，美国国立卫生研究院正在开展首个大型对照试验，以测试在患有呼吸衰竭的早产儿中使用振荡通气机进行高频通气的疗效。该试验结果将有助于明确高频通气的一些适应症及其在大量因呼吸窘迫综合征继发呼吸衰竭的婴儿中的效用。
