Reitzig P, Gütz H J, Apostoloff E, Irro F, Pilgrim G, Herbrandt I
Zentralinstitut für Krebsforschung der Akademie der Wissenschaften der DDR.
Dtsch Z Verdau Stoffwechselkr. 1987;47(3):101-4.
The authors tried to clarify relations between autoimmune gastritis and isolated atrophic corpus gastritis by bioptic corporal and antral examinations from 150 probands as well as examinations of gastrin in serum and parietal cell antibody tests. Only 30% of all patients examined with isolated atrophic gastritis of the corpus part revealed criteria of an autoimmune gastritis. Therefore investigations of antibodies against parietal cells are necessary to mark off both clinical pictures. This differentiation seems to be necessary regarding the high risk of gastric cancer following an autoimmune gastritis.
作者试图通过对150名受试者进行胃体和胃窦活检、血清胃泌素检测以及壁细胞抗体检测,来阐明自身免疫性胃炎与孤立性萎缩性胃体炎之间的关系。在所有接受检查的患有孤立性胃体萎缩性胃炎的患者中,只有30%表现出自身免疫性胃炎的标准。因此,有必要进行壁细胞抗体检测以区分这两种临床表现。考虑到自身免疫性胃炎后胃癌的高风险,这种区分似乎是必要的。