Il'inskiĭ O B, Spevak S E, Shekhter A B, Solov'eva A I, Titov M I
Farmakol Toksikol. 1987 Jul-Aug;50(4):64-6.
Synthetic analog of leucine enkephalin--hexapeptide dalargin was shown to stimulate healing of skin wounds in rats, dogs and mini-pigs at local and parenteral administration in doses of 0.1-100 micrograms/kg. Acceleration of proliferation with an increase of fibroblast mitoses, earlier and active growth of vascular elements, rapid maturation of granulation tissue and accelerated epithelialization were observed.
亮氨酸脑啡肽的合成类似物——六肽达洛argin被证明在大鼠、狗和小型猪身上以0.1 - 100微克/千克的剂量进行局部和肠胃外给药时，能刺激皮肤伤口愈合。观察到成纤维细胞有丝分裂增加，血管成分早期活跃生长，肉芽组织快速成熟和上皮化加速，从而促进了增殖。
