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Flavin radicals: chemistry and biochemistry.

作者信息

Müller F

机构信息

Department of Biochemistry, Agricultural University, Wageningen, The Netherlands.

出版信息

Free Radic Biol Med. 1987;3(3):215-30. doi: 10.1016/0891-5849(87)90009-8.

DOI:10.1016/0891-5849(87)90009-8

PMID:3311900

Abstract

The redox properties of free and protein-bound flavin are discussed extensively. The interaction of one and two-electron reduced flavin with oxygen is emphasized.

摘要

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告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

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Flavin radicals: chemistry and biochemistry.

作者信息

Müller F

机构信息

Department of Biochemistry, Agricultural University, Wageningen, The Netherlands.

出版信息

Free Radic Biol Med. 1987;3(3):215-30. doi: 10.1016/0891-5849(87)90009-8.

DOI:10.1016/0891-5849(87)90009-8

PMID:3311900

Abstract

The redox properties of free and protein-bound flavin are discussed extensively. The interaction of one and two-electron reduced flavin with oxygen is emphasized.

摘要

相似文献

1

Flavin radicals: chemistry and biochemistry.

Free Radic Biol Med. 1987;3(3):215-30. doi: 10.1016/0891-5849(87)90009-8.

2

The oxidation of catechols by reduced flavins and dehydrogenases. An electron spin resonance study of the kinetics and initial products of oxidation.还原型黄素和脱氢酶对儿茶酚的氧化作用。氧化动力学和初始产物的电子自旋共振研究。

J Biol Chem. 1973 Sep 10;248(17):6084-90.

3

The univalent reduction of oxygen by reduced flavins and quinones.黄素和醌还原物对氧的单价还原作用。

J Biol Chem. 1972 Jan 10;247(1):188-92.

4

Model studies on flavin-dependent oxidoreduction.

Vitam Horm. 1970;28:467-87. doi: 10.1016/s0083-6729(08)60907-3.

5

The acceptor specificity of flavins and flavoproteins. 3. Flavoproteins.黄素和黄素蛋白的受体特异性。3. 黄素蛋白。

Biochim Biophys Acta. 1971 Mar 2;226(2):269-84. doi: 10.1016/0005-2728(71)90094-6.

6

The acceptor specificity of flavins and flavoproteins. II. Free flavins.黄素和黄素蛋白的受体特异性。II. 游离黄素

Biochim Biophys Acta. 1971 Mar 2;226(2):259-68. doi: 10.1016/0005-2728(71)90093-4.

7

Flavin and 5-deazaflavin: a chemical evaluation of 'modified' flavoproteins with respect to the mechanisms of redox biocatalysis.黄素与5-脱氮黄素：关于氧化还原生物催化机制的“修饰”黄素蛋白的化学评估

FEBS Lett. 1977 Dec 1;84(1):5-21. doi: 10.1016/0014-5793(77)81047-8.

8

Flavin-O2 interaction mechanisms and the function of flavin in hydroxylation reactions.黄素与氧气的相互作用机制以及黄素在羟基化反应中的功能。

Ann N Y Acad Sci. 1973;212:13-26. doi: 10.1111/j.1749-6632.1973.tb47583.x.

9

Ultrafast photooxidation of protein-bound anionic flavin radicals.超快光氧化法使蛋白结合态阴离子黄素自由基失活。

Proc Natl Acad Sci U S A. 2022 Feb 22;119(8). doi: 10.1073/pnas.2118924119.

10

STRUCTURE AND FUNCTION OF IRON-FLAVOPROTEINS.铁黄素蛋白的结构与功能。

Fed Proc. 1964 Jan-Feb;23:30-8.

引用本文的文献

1

Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.核黄素缺乏可导致 RPE 细胞发生不可逆转的变化，并通过改变细胞代谢动态平衡破坏视网膜功能。

Redox Biol. 2022 Aug;54:102375. doi: 10.1016/j.redox.2022.102375. Epub 2022 Jun 16.

2

Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme.串联晶体学捕获黄素酶中顺序电子和质子转移事件的动态控制。

Nat Chem. 2022 Jun;14(6):677-685. doi: 10.1038/s41557-022-00922-3. Epub 2022 Apr 7.

3

Structural Features of Cytochrome -Cytochrome Reductase Complex Formation and Implications for the Intramolecular Dynamics of Cytochrome Reductase.

相似文献

1

Flavin radicals: chemistry and biochemistry.

Free Radic Biol Med. 1987;3(3):215-30. doi: 10.1016/0891-5849(87)90009-8.

2

The oxidation of catechols by reduced flavins and dehydrogenases. An electron spin resonance study of the kinetics and initial products of oxidation.还原型黄素和脱氢酶对儿茶酚的氧化作用。氧化动力学和初始产物的电子自旋共振研究。

J Biol Chem. 1973 Sep 10;248(17):6084-90.

3

The univalent reduction of oxygen by reduced flavins and quinones.黄素和醌还原物对氧的单价还原作用。

J Biol Chem. 1972 Jan 10;247(1):188-92.

4

Model studies on flavin-dependent oxidoreduction.

Vitam Horm. 1970;28:467-87. doi: 10.1016/s0083-6729(08)60907-3.

5

The acceptor specificity of flavins and flavoproteins. 3. Flavoproteins.黄素和黄素蛋白的受体特异性。3. 黄素蛋白。

Biochim Biophys Acta. 1971 Mar 2;226(2):269-84. doi: 10.1016/0005-2728(71)90094-6.

6

The acceptor specificity of flavins and flavoproteins. II. Free flavins.黄素和黄素蛋白的受体特异性。II. 游离黄素

Biochim Biophys Acta. 1971 Mar 2;226(2):259-68. doi: 10.1016/0005-2728(71)90093-4.

7

Flavin and 5-deazaflavin: a chemical evaluation of 'modified' flavoproteins with respect to the mechanisms of redox biocatalysis.黄素与5-脱氮黄素：关于氧化还原生物催化机制的“修饰”黄素蛋白的化学评估

FEBS Lett. 1977 Dec 1;84(1):5-21. doi: 10.1016/0014-5793(77)81047-8.

8

Flavin-O2 interaction mechanisms and the function of flavin in hydroxylation reactions.黄素与氧气的相互作用机制以及黄素在羟基化反应中的功能。

Ann N Y Acad Sci. 1973;212:13-26. doi: 10.1111/j.1749-6632.1973.tb47583.x.

9

Ultrafast photooxidation of protein-bound anionic flavin radicals.超快光氧化法使蛋白结合态阴离子黄素自由基失活。

Proc Natl Acad Sci U S A. 2022 Feb 22;119(8). doi: 10.1073/pnas.2118924119.

10

STRUCTURE AND FUNCTION OF IRON-FLAVOPROTEINS.铁黄素蛋白的结构与功能。

Fed Proc. 1964 Jan-Feb;23:30-8.

引用本文的文献

1

Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.核黄素缺乏可导致 RPE 细胞发生不可逆转的变化，并通过改变细胞代谢动态平衡破坏视网膜功能。

Redox Biol. 2022 Aug;54:102375. doi: 10.1016/j.redox.2022.102375. Epub 2022 Jun 16.

2

Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme.串联晶体学捕获黄素酶中顺序电子和质子转移事件的动态控制。

Nat Chem. 2022 Jun;14(6):677-685. doi: 10.1038/s41557-022-00922-3. Epub 2022 Apr 7.

3

Structural Features of Cytochrome -Cytochrome Reductase Complex Formation and Implications for the Intramolecular Dynamics of Cytochrome Reductase.

细胞色素 - 细胞色素还原酶复合物形成的结构特征及其对细胞色素还原酶分子内动力学的影响

Int J Mol Sci. 2021 Dec 23;23(1):118. doi: 10.3390/ijms23010118.

4

The diverse functionality of NQO1 and its roles in redox control.NQO1 的多样化功能及其在氧化还原控制中的作用。

Redox Biol. 2021 May;41:101950. doi: 10.1016/j.redox.2021.101950. Epub 2021 Mar 20.

5

Flavins Act as a Critical Liaison Between Metabolic Homeostasis and Oxidative Stress in the Retina.黄素在视网膜代谢稳态与氧化应激之间起关键联络作用。

Front Cell Dev Biol. 2020 Aug 27;8:861. doi: 10.3389/fcell.2020.00861. eCollection 2020.

6

Ultrafast flavin/tryptophan radical pair kinetics in a magnetically sensitive artificial protein.超快黄素/色氨酸自由基对在磁性敏感人工蛋白质中的动力学。

Phys Chem Chem Phys. 2019 Jun 26;21(25):13453-13461. doi: 10.1039/c9cp01916b.

7

Flavin homeostasis in the mouse retina during aging and degeneration.衰老和变性过程中小鼠视网膜中的黄素稳态。

J Nutr Biochem. 2018 Dec;62:123-133. doi: 10.1016/j.jnutbio.2018.09.003. Epub 2018 Sep 15.

8

Metabolic shift at the class level sheds light on adaptation of methanogens to oxidative environments.在类水平上的代谢转变揭示了产甲烷菌对氧化环境的适应。

ISME J. 2018 Feb;12(2):411-423. doi: 10.1038/ismej.2017.173. Epub 2017 Nov 14.

9

Functions of NQO1 in Cellular Protection and CoQ Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.NQO1在细胞保护和辅酶Q代谢中的功能及其作为氧化还原敏感分子开关的潜在作用。

Front Physiol. 2017 Aug 24;8:595. doi: 10.3389/fphys.2017.00595. eCollection 2017.

10

Proton transfer to flavin stabilizes the signaling state of the blue light receptor plant cryptochrome.质子转移至黄素可稳定蓝光受体植物隐花色素的信号传导状态。

J Biol Chem. 2015 Jan 16;290(3):1743-51. doi: 10.1074/jbc.M114.606327. Epub 2014 Dec 3.

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Flavin radicals: chemistry and biochemistry.

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Flavin radicals: chemistry and biochemistry.

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机构信息

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