State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Road, Guangzhou, China.
School of Nursing, Sun Yat-sen University, No. 74 Zhongshan Second Road, Guangzhou, China.
Eur J Oncol Nurs. 2020 Dec;49:101836. doi: 10.1016/j.ejon.2020.101836. Epub 2020 Sep 17.
The aim of this study was to evaluate the effects of home-based exercise on exercise capacity, cancer-related fatigue, insomnia, pain, appetite loss, coughing, anxiety, depression, and quality of life of patients with lung cancer.
We conducted a search using English and Chinese databases, namely PubMed, Web of Science, Embase, ProQuest, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature (CBM), Wanfang Data, and China Science and Technology Journal Database (VIP) up to December 4, 2018. We selected randomized controlled trials and quasi-experimental trials that compared the effects of home-based exercise and routine guidance on exercise capacity, cancer-related fatigue, insomnia, pain, appetite loss, coughing, anxiety, depression, and quality of life of patients with lung cancer. The effect size was calculated using mean difference and 95% confidence interval, data were analyzed using the Stata version 12.0 software.
We retrieved seven randomized controlled trials and seven quasi-experimental trials involving 694 patients in total. Home-based exercise significantly improved exercise capacity, reduced cancer-related fatigue, insomnia, anxiety, and depression, and improved quality of life (P < .05). However, it did not significantly reduce pain, appetite loss, and coughing symptoms (P > .05).
Home-based exercise is a beneficial approach to improving exercise capacity, some symptoms, and quality of life of patients with lung cancer. Home-based exercise should be routinely recommended by health professionals when patients with lung cancer are discharged from hospital.
本研究旨在评估基于家庭的运动对肺癌患者运动能力、癌因性疲乏、失眠、疼痛、食欲减退、咳嗽、焦虑、抑郁和生活质量的影响。
我们使用英文和中文数据库（包括 PubMed、Web of Science、Embase、ProQuest、Cochrane 图书馆、中国国家知识基础设施（CNKI）、中国生物医学文献（CBM）、万方数据和中国科技期刊数据库（VIP））进行了检索，检索时间截至 2018 年 12 月 4 日。我们选择了比较基于家庭的运动和常规指导对肺癌患者运动能力、癌因性疲乏、失眠、疼痛、食欲减退、咳嗽、焦虑、抑郁和生活质量影响的随机对照试验和准实验研究。使用均数差和 95%置信区间来计算效应量，使用 Stata 版本 12.0 软件进行数据分析。
我们共检索到 7 项随机对照试验和 7 项准实验研究，共纳入 694 例患者。基于家庭的运动显著改善了运动能力，减轻了癌因性疲乏、失眠、焦虑和抑郁，并提高了生活质量（P<.05）。但对疼痛、食欲减退和咳嗽症状没有明显改善（P>.05）。
基于家庭的运动是改善肺癌患者运动能力、部分症状和生活质量的有益方法。当肺癌患者出院时，健康专业人员应常规推荐基于家庭的运动。
