University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Clyra Medical Technologies, Inc., Tampa, Florida, USA.
F1000Res. 2020 Jul 3;9:674. doi: 10.12688/f1000research.24651.2. eCollection 2020.
The ability to protect workers and healthcare professionals from infection by SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is of great concern. Hospitals, nursing homes and employers are adopting infection control strategies based on guidance from leading public health organizations such as the CDC, OSHA, FDA, and other government bodies. Certain hard surface disinfectants are effective against SARS-CoV-2 but are not suitable for use on skin or personal protective equipment (PPE) that comes into contact with skin. Furthermore, near-ubiquitous alcohol-based hand sanitizers are acceptable for use on skin, but they are not suitable for use on PPE. PPE, especially masks, are also commonly being used for longer durations than normal. There is a need for new products and techniques that can effectively disinfect PPE during wear time without having detrimental effects on surrounding skin. Clyraguard spray is a novel copper iodine complex designed to be used on non-critical PPE. In this study, the Clyraguard copper iodine complex was tested for its ability to inactivate SARS-CoV-2 in solution. These data indicate the product to be effective in reducing SARS-CoV-2 titers in a time-dependent manner, with the virus being reduced below the detection limits within 30 minutes. These results suggest that Clyraguard may be an effective tool for mitigating cross-contamination of non-critical PPE that may come into contact with SARS-CoV-2.
保护工人和医护人员免受感染 SARS-CoV-2(导致 2019 年冠状病毒病(COVID-19)的病毒)的能力是非常重要的。医院、养老院和雇主正在根据美国疾病控制与预防中心(CDC)、职业安全与健康管理局(OSHA)、食品和药物管理局(FDA)和其他政府机构等主要公共卫生组织的指导,采取感染控制策略。某些硬表面消毒剂对 SARS-CoV-2 有效,但不适合用于接触皮肤的个人防护装备(PPE)。此外,无处不在的酒精类洗手液可用于皮肤,但不适合用于 PPE。PPE,尤其是口罩,也经常被长时间使用。因此,需要开发新产品和技术,以便在佩戴时能够有效地对 PPE 进行消毒,而不会对周围皮肤造成不利影响。Clyraguard 喷雾是一种新型的铜碘复合物,旨在用于非关键 PPE。在这项研究中,测试了 Clyraguard 铜碘复合物在溶液中灭活 SARS-CoV-2 的能力。这些数据表明,该产品能够以时间依赖性方式有效降低 SARS-CoV-2 的滴度,病毒在 30 分钟内降低到检测限以下。这些结果表明,Clyraguard 可能是一种有效工具,可以减轻可能接触到 SARS-CoV-2 的非关键 PPE 的交叉污染。