Temur Bahar, Aydın Selim, Suzan Dilek, Kırat Barış, Demir Ibrahim Halil, Erek Ersin
Department of Cardiovascular Surgery, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Turkey.
Department of Cardiovascular Surgery, Gaziosmanpaşa Hospital, Yeni Yüzyıl University, Istanbul, Turkey.
J Card Surg. 2021 Jan;36(1):56-61. doi: 10.1111/jocs.15133. Epub 2020 Oct 30.
Transannular patch, which results in pulmonary insufficiency (PI), is usually required during repair of tetralogy of fallot (TOF). In this study, we compared three types of pulmonary valve reconstruction techniques during transannular repair of TOF.
Between February 2014 and January 2018, 50 patients with TOF underwent primary repair with transannular patch. These patients were divided into three groups. In Group 1, (n = 15), a single gluteraldehyde-treated autologous pericardial patch (standard method) was reconstructed as monocusp. In Group 2, (n = 16) Nunn's bileaflet pulmonary valve reconstruction technique was used with pericardial patch. In Group 3, (n = 19), Nunn's bileaflet technique was performed with expanded polytetrafluoroethylene membrane. The outcomes of the patients and early and midterm competency of the pulmonary valves were analyzed.
These techniques were significantly effective in early postoperative period. Freedom from moderate to severe PI were 73.3%; 100% and 89.4%, respectively. Mortality, duration of intensive care unit and hospital stay were similar between the groups. The mean follow-up period was 17.5 ± 13.0 (3-57) months. Freedom from moderate to severe PI decreased to 40%; 81.2% and 73.7%, respectively at the end of the follow-up period. Presence of moderate to severe PI was significantly higher in Group 1 (p = .018 between Groups 1 and 2, p = .048 between Groups 1 and 3).
All three pulmonary valve reconstruction techniques provided competent pulmonary valves. Nunn's bileaflet technique had better outcome at midterm. It has a potential to delay right ventricular dysfunction at long-term.
法洛四联症(TOF)修复术中通常需要使用经环补片,这会导致肺动脉瓣关闭不全(PI)。在本研究中,我们比较了TOF经环修复术中三种类型的肺动脉瓣重建技术。
2014年2月至2018年1月期间,50例TOF患者接受了经环补片一期修复术。这些患者被分为三组。第1组(n = 15),使用单个经戊二醛处理的自体心包补片(标准方法)重建为单叶瓣。第2组(n = 16),采用心包补片的Nunn双叶肺动脉瓣重建技术。第3组(n = 19),使用膨体聚四氟乙烯膜进行Nunn双叶技术。分析了患者的结局以及肺动脉瓣的早期和中期功能。
这些技术在术后早期显著有效。中度至重度PI的无事件生存率分别为73.3%、100%和89.4%。各组之间的死亡率、重症监护病房时长和住院时间相似。平均随访期为17.5±13.0(3 - 57)个月。随访期末,中度至重度PI的无事件生存率分别降至40%、81.2%和73.7%。第1组中度至重度PI的发生率显著更高(第1组和第2组之间p = 0.018,第1组和第3组之间p = 0.048)。
所有三种肺动脉瓣重建技术均能提供功能良好的肺动脉瓣。Nunn双叶技术在中期有更好的结局。它有可能在长期延迟右心室功能障碍。