Hospital Materno-Infantil Carlos Haya, Málaga, España.
Rev Esp Cardiol. 2010 Dec;63(12):1438-43. doi: 10.1016/s1885-5857(10)70278-4.
To report on our initial experience with the implantation of a pulmonary valve using Nunn's technique in association with a transannular patch for the complete repair of the tetralogy of Fallot.
In total, 21 patients were treated between September 2008 and February 2010. Their ages ranged from 7 months to 15 years (median 12 months) and weights from 6.8 kg to 44 kg (median 10 kg). Four patients had previously undergone palliative shunt placement; in two, it was associated with the diagnosis of a complete atrioventricular septal defect. Use of the transannular patch (treated autologous pericardium) was preceded by implantation of a 0.1-mm polytetrafluoroethylene (PTFE) monocusp valve using posterior fixation. Intraoperative transesophageal echocardiography and pressure gradient measurement were carried out, and echocardiography was repeated before discharge.
No deaths were recorded. One patient had a residual ventricular septal defect that required reintervention. Echocardiography showed that the maximum gradient across the PTFE valve was 25 mmHg. Regurgitation was mild in 19 cases and moderate in 2 (the first and second in the series).
Initial results using a transannular patch with a modified monocusp valve to repair the outflow tract in the tetralogy of Fallot were promising: there was only a slight pressure gradient and mild regurgitation. A medium-or long-term follow-up study is required to confirm these findings and to compare them with results obtained using other techniques.
报告我们使用 Nunn 技术植入肺动脉瓣,并结合跨瓣环补片进行完全修复法洛四联症的初步经验。
2008 年 9 月至 2010 年 2 月,共治疗 21 例患者。年龄 7 个月至 15 岁(中位数 12 个月),体重 6.8 公斤至 44 公斤(中位数 10 公斤)。4 例患者曾行姑息性分流术,其中 2 例合并完全性房室间隔缺损。在植入 0.1 毫米厚聚四氟乙烯(PTFE)单瓣前,先使用跨瓣环补片(处理自体心包)。术中进行经食管超声心动图和压力梯度测量,并在出院前重复进行超声心动图检查。
无死亡病例。1 例患者残留室间隔缺损需再次介入治疗。超声心动图显示 PTFE 瓣最大跨瓣梯度为 25mmHg。19 例瓣反流轻度,2 例中度(第 1 例和第 2 例)。
使用改良的单瓣和跨瓣环补片修复法洛四联症流出道的初步结果令人鼓舞:仅存在轻度压力梯度和轻度瓣反流。需要进行中长期随访研究以证实这些发现,并与使用其他技术的结果进行比较。