Department of Oral and Maxillofacial Surgery/Pathology Amsterdam University Medical Center/ Academic Center for Dentistry (ACTA) P.O. Box 7057, 1007MB, Amsterdam, the Netherlands
Med Oral Patol Oral Cir Bucal. 2020 Nov 1;25(6):e834-e837. doi: 10.4317/medoral.24334.
A series of 20 consecutive patients with an osteosarcoma of the jaws has been evaluated with regard to possible professional diagnostic delay. When set at an arbitrarily chosen period beyond three months, professional delay occurred in 15 patients, the mean being 21 months and the median 11 months. In five of the 15 patients a wrong diagnosis has been rendered on the biopsy specimen, being fibrous dysplasia (2x), osteoma (2x) and, in case of palatomaxillary swelling, pleomorphic adenoma (1x). In the other ten patients the initial clinicoradiographic features were misleading and apparently not indicative of a malignancy, except for one patient in whom a distinct widening of the periodontal ligament, as expressed on a periapical film, has been overlooked or not properly interpreted. It has not been possible to assess the possible influence of the delayed diagnosis on the prognosis.
已对 20 例连续颌骨骨肉瘤患者进行了专业诊断延迟的评估。如果将时间设定为任意选择的三个月以上，则 15 例患者出现了专业延迟，平均为 21 个月，中位数为 11 个月。在这 15 名患者中，5 名患者的活检标本做出了错误的诊断，分别为纤维结构不良（2x）、骨瘤（2x），而对于腭上颌肿胀，诊断为多形性腺瘤（1x）。在另外 10 名患者中，初始临床和影像学特征具有误导性，并且显然不提示恶性肿瘤，除了一名患者的牙周膜明显增宽（在根尖片上表现）被忽视或未正确解释。尚未能够评估延迟诊断对预后的可能影响。
