Division of Gastroenterology and Hepatology, Stanford School of Medicine, Stanford, CA, USA; Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, USA.
Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, USA; Center for Human Microbiome Studies, Stanford School of Medicine, Stanford, CA, USA.
Cell. 2020 Oct 29;183(3):589-591. doi: 10.1016/j.cell.2020.10.008.
Ha and colleagues describe a previously unappreciated diversity of microbes in the mesenteric adipose tissue (MAT) surrounding the GI tract. Viable bacteria that are mislocalized from the gut microbiota and metabolically adapted to the MAT contribute to the "creeping fat" of Crohn's disease.
哈及其同事描述了胃肠道周围肠系膜脂肪组织(MAT)中以前未被重视的微生物多样性。从肠道微生物群错位定位并适应 MAT 代谢的存活细菌导致了克罗恩病的“ creeping fat”。