Suppr超能文献

当肠道菌群潜入脂肪时,脂肪也会卷土重来。

When Gut Microbiota Creep into Fat, the Fat Creeps Back.

机构信息

Division of Gastroenterology and Hepatology, Stanford School of Medicine, Stanford, CA, USA; Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, USA.

Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, USA; Center for Human Microbiome Studies, Stanford School of Medicine, Stanford, CA, USA.

出版信息

Cell. 2020 Oct 29;183(3):589-591. doi: 10.1016/j.cell.2020.10.008.

Abstract

Ha and colleagues describe a previously unappreciated diversity of microbes in the mesenteric adipose tissue (MAT) surrounding the GI tract. Viable bacteria that are mislocalized from the gut microbiota and metabolically adapted to the MAT contribute to the "creeping fat" of Crohn's disease.

摘要

哈及其同事描述了胃肠道周围肠系膜脂肪组织(MAT)中以前未被重视的微生物多样性。从肠道微生物群错位定位并适应 MAT 代谢的存活细菌导致了克罗恩病的“ creeping fat”。

相似文献

1
When Gut Microbiota Creep into Fat, the Fat Creeps Back.
Cell. 2020 Oct 29;183(3):589-591. doi: 10.1016/j.cell.2020.10.008.
2
Creeping Fat in Crohn's Disease: Innocuous or innocuum?
Immunity. 2020 Nov 17;53(5):905-907. doi: 10.1016/j.immuni.2020.10.018.
3
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.
Cell. 2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009. Epub 2020 Sep 28.
4
Creeping fat in Crohn's disease explained.
Nat Rev Gastroenterol Hepatol. 2020 Dec;17(12):713. doi: 10.1038/s41575-020-00379-0.
5
Creeping Fat in the Pathogenesis of Crohn's Disease: An Orchestrator or a Silent Bystander?
Inflamm Bowel Dis. 2023 Nov 2;29(11):1826-1836. doi: 10.1093/ibd/izad095.
7
Microbiota in mesenteric adipose tissue from Crohn's disease promote colitis in mice.
Microbiome. 2021 Nov 23;9(1):228. doi: 10.1186/s40168-021-01178-8.
10
Visceral fat and gut inflammation.
Nutrition. 2012 Feb;28(2):113-7. doi: 10.1016/j.nut.2011.09.009.

引用本文的文献

2
Fecal microbiota and metabolites in the pathogenesis and precision medicine for inflammatory bowel disease.
Precis Clin Med. 2024 Sep 23;7(3):pbae023. doi: 10.1093/pcmedi/pbae023. eCollection 2024 Sep.
3
Intestinal microbiota in the treatment of metabolically associated fatty liver disease.
World J Clin Cases. 2022 Nov 6;10(31):11240-11251. doi: 10.12998/wjcc.v10.i31.11240.
5
The development and structure of the mesentery.
Commun Biol. 2021 Aug 18;4(1):982. doi: 10.1038/s42003-021-02496-1.
6
Contribution of Adipose Tissue to the Chronic Immune Activation and Inflammation Associated With HIV Infection and Its Treatment.
Front Immunol. 2021 Jun 18;12:670566. doi: 10.3389/fimmu.2021.670566. eCollection 2021.

本文引用的文献

1
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.
Cell. 2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009. Epub 2020 Sep 28.
2
Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease.
Front Cardiovasc Med. 2020 Feb 25;7:22. doi: 10.3389/fcvm.2020.00022. eCollection 2020.
3
The gut microbiome and metabolic syndrome.
J Clin Invest. 2019 Oct 1;129(10):4050-4057. doi: 10.1172/JCI129194.
4
The mesentery: structure, function, and role in disease.
Lancet Gastroenterol Hepatol. 2016 Nov;1(3):238-247. doi: 10.1016/S2468-1253(16)30026-7. Epub 2016 Oct 12.
5
Inflammation, metaflammation and immunometabolic disorders.
Nature. 2017 Feb 8;542(7640):177-185. doi: 10.1038/nature21363.
6
Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches.
Gastroenterology. 2017 Feb;152(2):327-339.e4. doi: 10.1053/j.gastro.2016.10.012. Epub 2016 Oct 18.
7
Bacterial translocation - impact on the adipocyte compartment.
Front Immunol. 2014 Jan 6;4:510. doi: 10.3389/fimmu.2013.00510.
8
Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's disease.
Gut. 2012 Jan;61(1):78-85. doi: 10.1136/gutjnl-2011-300370. Epub 2011 Sep 21.
10
[Bacterial translocation in Crohn disease].
Gastroenterol Clin Biol. 1992;16(10):777-81.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验