Black Steve, Bloom David E, Kaslow David C, Pecetta Simone, Rappuoli Rino
Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.
Harvard T.H. Chan School of Public Health, Harvard University, Boston MA 02115, USA.
Semin Immunol. 2020 Aug;50:101413. doi: 10.1016/j.smim.2020.101413. Epub 2020 Oct 28.
The urgency to develop vaccines against Covid-19 is putting pressure on the long and expensive development timelines that are normally required for development of lifesaving vaccines. There is a unique opportunity to take advantage of new technologies, the smart and flexible design of clinical trials, and evolving regulatory science to speed up vaccine development against Covid-19 and transform vaccine development altogether.
研发针对新冠病毒的疫苗的紧迫性，正给通常研发挽救生命的疫苗所需的漫长且昂贵的研发时间线带来压力。现在有一个独特的机会，可以利用新技术、临床试验的灵活巧妙设计以及不断发展的监管科学，来加速针对新冠病毒的疫苗研发，并彻底改变疫苗研发的整体状况。
