Deletion of c-fms sequences in the 5q- syndrome.
作者信息
Bartram C R, Böhlke J V, Adolph S, Hameister H, Ganser A, Anger B, Heisterkamp N, Groffen J
机构信息
Department of Pediatrics II, University of Ulm, Federal Republic of Germany.
出版信息
Leukemia. 1987 Feb;1(2):146-9.
PMID:3312836
Abstract
Southern blot analyses demonstrated hemizygosity of c-fms sequences in three cases of the 5q- syndrome, cytogenetically characterized by del(5)(q13;q35) or del(5)(q31;q35). In situ hybridization studies revealed a deletion of this oncogene from the 5q- chromosome in two cases; moreover, we localized c-fms to region 5q31-33.
摘要
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