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肺康复治疗对改善肺癌患者肺叶切除术后呼吸运动能力和减轻呼吸困难的影响:一项临床研究。

Effects of Lung Rehabilitation Therapy in Improving Respiratory Motor Ability and Alleviating Dyspnea in Patients with Lung Cancer After Lobectomy: A Clinical Study.

出版信息

Altern Ther Health Med. 2022 Mar;28(3):18-23.

PMID:33128535
Abstract

PURPOSE

The primacy aim of our study was to identify the effect of lung rehabilitation therapy on improving respiratory motor ability and alleviating dyspnea in patients with lung cancer after lobectomy.

METHODS

The prospective study included a total of 58 patients with lung cancer who underwent lobectomy in our hospital from February 2017 to 2018. The patients were randomly divided into observation group (n = 29) and control group (n = 29). Patients in the control group were treated with routine nursing after operation, and patients in the observation group received lung rehabilitation therapy in combination with routine nursing. The pulmonary function, respiratory function and exercise ability of the patients in the two groups were compared, and fasting venous blood was taken before and after the beginning of the study. Moreover, the related serum factors were detected by enzyme-linked immunosorbent assay (Elisa).

RESULTS

After treatment, the percentage of FEV1 and FEV1/FVC in the predicted value in the observation group was significantly different compared to that before treatment. The CAT score and exercise endurance score in the observation group showed significant difference compared to those in the control group. Compared with patients in the control group, the average hospitalization time of patients in the observation group was reduced by 2 days, and the probability of pulmonary complications decreased from 13.8% to 3.4%, with an average decrease of 10.4%. Additionally, the patients with pulmonary complications were reduced by 3 cases, and the retention time of chest tube was also remarkably reduced. CRP, IL-6 and TNF-α in serum of the observation group were significantly improved, with statistical difference.

CONCLUSION

Lung rehabilitation therapy is an effective approach for the recovery of motor ability and respiratory function of postoperative patients. A simple lung rehabilitation exercise training program can significantly improve the exercise tolerance of respiration for patients, alleviate dyspnea, hence improve their quality of life. In addition, routine nursing in the combination of lung rehabilitation therapy exerted greater beneficial effect in terms of reducing the inflammation and achieving improved life quality of patients.

摘要

目的

本研究的首要目的是确定肺康复治疗对改善肺癌患者肺叶切除术后呼吸运动能力和缓解呼吸困难的影响。

方法

前瞻性研究共纳入 2017 年 2 月至 2018 年在我院行肺叶切除术的 58 例肺癌患者,随机分为观察组(n=29)和对照组(n=29)。对照组患者术后给予常规护理,观察组患者在常规护理的基础上给予肺康复治疗。比较两组患者的肺功能、呼吸功能和运动能力,于研究开始前及开始后空腹抽取静脉血,采用酶联免疫吸附法(ELISA)检测相关血清因子。

结果

治疗后,观察组患者的 FEV1 及 FEV1/FVC 预计值百分比与治疗前比较差异有统计学意义,观察组患者的 CAT 评分及运动耐力评分与对照组比较差异有统计学意义。与对照组患者比较,观察组患者的平均住院时间缩短 2 天,肺部并发症发生率从 13.8%下降至 3.4%,平均下降 10.4%,肺部并发症减少 3 例,胸腔引流管留置时间也明显缩短。观察组患者的血清 CRP、IL-6 和 TNF-α明显改善,差异有统计学意义。

结论

肺康复治疗是促进术后患者运动能力和呼吸功能恢复的有效方法。简单的肺康复运动训练方案可显著提高患者的呼吸运动耐力,缓解呼吸困难,从而提高生活质量。此外,肺康复治疗联合常规护理在减轻炎症和提高患者生活质量方面具有更大的有益效果。

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