Department of Neurosurgery, Oakland University William Beaumont, School of Medicine, Royal Oak, Michigan, USA.
Department of Neurosurgery, Oakland University William Beaumont, School of Medicine, Royal Oak, Michigan, USA.
World Neurosurg. 2021 Feb;146:e544-e554. doi: 10.1016/j.wneu.2020.10.126. Epub 2020 Oct 28.
Few studies have investigated the financial influence of surgical site local morselized bone autograft (LMBA) on the overall cost of spinal arthrodesis procedures. The purpose of this study is to evaluate the potential savings from introducing LMBA in spinal fusion procedures compared with no LMBA use.
Retrospectively, cost analysis was conducted on a single-center data collected from 266 patients who underwent minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) ranging from L1 through S1 during a period of approximately 4 years. Cost data were obtained from individual patient invoices from the distributor. Sensitivity analyses were also conducted for different costs of allograft and LMBA.
A total of 282 levels were grafted in 266 subjects. The total quantity of LMBA harvested was 2433.5 mL, and a total of 1610 mL of allograft (Trinity Elite, ORTHOFIX, Lewisville, Texas, USA) were used. The overall cost savings from introducing LMBA in MI-TLIF surgery were $1,094,931 over the 4-year period with mean direct cost saving of $4116.28 per patient based on reduction in allograft. Results for cost savings per patient were sensitive to different direct costs of allograft and LMBA. A >95% fusion rate was achieved based on dynamic radiographs evaluated by an independent radiologist.
LMBA is a cost-saving bone graft extender option in MI-TLIF procedures while achieving high fusion rates. The savings are mainly achieved by reducing the amount of allograft needed and subsequent reduction in the total bone graft costs. Further research needs to be performed regarding long-term economic benefit.
很少有研究调查手术部位局部碎骨自体移植物(LMBA)对脊柱关节融合术整体成本的财务影响。本研究旨在评估与不使用 LMBA 相比,在脊柱融合术中引入 LMBA 的潜在节省。
回顾性地对 266 例接受微创经椎间孔腰椎椎间融合术(MI-TLIF)的患者进行了单中心数据的成本分析,这些患者在大约 4 年的时间内从 L1 到 S1 进行了手术。成本数据来自经销商的每位患者发票。还对同种异体移植物和 LMBA 的不同成本进行了敏感性分析。
266 例患者共进行了 282 个节段的植骨。共采集 LMBA 2433.5 毫升,使用了 1610 毫升同种异体移植物(美国德克萨斯州刘易斯维尔的 ORTHOFIX 的 Trinity Elite)。在 4 年期间,通过引入 MI-TLIF 手术中的 LMBA,总体节省了 1094931 美元的成本,平均每位患者的直接成本节省了 4116.28 美元,这是由于同种异体移植物的减少。基于对异体移植物的直接成本和 LMBA 的不同,每位患者的节省成本结果存在敏感性。通过独立放射科医生评估的动态射线照片,实现了 >95%的融合率。
在 MI-TLIF 手术中,LMBA 是一种节省成本的骨移植物扩展选择,同时可以实现高融合率。节省主要是通过减少所需同种异体移植物的量和随后降低总骨移植成本来实现的。需要进一步研究长期经济效益。