Department of Gynecology and Obstetrics, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
Department of Gynecology and Obstetrics, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
J Pediatr Adolesc Gynecol. 2021 Feb;34(1):6-11. doi: 10.1016/j.jpag.2020.10.006. Epub 2020 Oct 29.
To assess the prevalence of cytological abnormalities among young people from a large population in the city of São Paulo (Brazil).
Retrospective, observational analysis of data from the institution's data processing center.
A private laboratory in São Paulo (Brazil).
Comparison of 3 different groups (ie, adolescent women [aged ≤19 years], young adult women [aged between 20 and 24 years], and adult women [aged 25 years and older]).
Assessment of results from all cervical-vaginal smears collected for cytology between January 2010 and December 2015.
Comparative analysis of cytological abnormalities in the 3 different groups.
A total of 1,026,671 satisfactory cytology tests were performed. The proportion of cytological abnormalities was found to decrease with age (P < .001) and was similar in the groups comprised of adolescents and young adults, with 3.405/ 20.921 (16.3%) and 13,635/ 78,277 (17.4%), respectively, and 74,320/ 927,473 (8.0%) in the group of adult patients (P < .001). Among the positive cytologies in the group of adolescents, 3,331/ 3,405 (97.8%) represented low-grade lesions and 74/ 3,405 (2.2%) high-grade lesions, whereas among adults older than 25 years old, these figures were 69,092/ 74.320 (93%) and 5,228/ 74.320 (6.9%), respectively. No cases of cancer were found in the group of adolescents.
Cytological screening of young people is not recommended because of the low prevalence of high-grade cytological abnormalities in this population, with cancer being a rare event. This inadvertent screening could lead to unnecessary complementary exams and overtreatment, which could compromise the reproductive future of these young women.
评估巴西圣保罗市大量人群中年轻人的细胞学异常发生率。
对机构数据处理中心数据的回顾性、观察性分析。
巴西圣保罗的一家私人实验室。
比较了 3 个不同的组（即青少年女性（年龄≤19 岁）、年轻成年女性（年龄在 20 岁至 24 岁之间）和成年女性（年龄在 25 岁及以上））。
评估 2010 年 1 月至 2015 年 12 月期间所有用于细胞学检查的宫颈阴道涂片的结果。
3 个不同组的细胞学异常比较分析。
共进行了 1026671 次满意的细胞学检查。细胞学异常的比例随年龄的增加而降低（P<.001），青少年和年轻成年人组成的组之间无差异，分别为 3.405/20.921（16.3%）和 13635/78277（17.4%），而成年患者组为 74320/927473（8.0%）（P<.001）。在青少年组的阳性细胞学中，3331/3405（97.8%）为低级别病变，74/3405（2.2%）为高级别病变，而在 25 岁以上的成年组中，这些数字分别为 69092/74320（93%）和 5228/74320（6.9%）。在青少年组中未发现癌症病例。
由于该人群中高级别细胞学异常的发生率较低，且癌症是一种罕见事件，因此不建议对年轻人进行细胞学筛查。这种无意中的筛查可能导致不必要的补充检查和过度治疗，从而影响这些年轻女性的生殖未来。
