Peng Matthew JianQiao, Cao XiongWei, Chen Hai-Yan, Hu Yong, Li XinXu, Lao YongQiang, Bai Bo
Orthopedics Dept. of 1st Affiliated Hospital, GuangZhou Medical University, China.
ENT Dept. Guanghai Central Hospital, Taishan, Guangdong, China.
Comput Methods Programs Biomed. 2021 Jan;198:105775. doi: 10.1016/j.cmpb.2020.105775. Epub 2020 Oct 3.
To compare mechanical properties of femoral tumor treatments so that better operative strategy for limb tumors surgery is optimized.
Fourteen femoral CT images were randomly selected to rebuild 3D models by MIMICS. They were then executed by reverse engineering softwares for simulative modes. Mode #1: Intralesional curettage with cement filled plus fixator; Mode #2: Distal femur resection with tumorous prosthesis replaced. Finally, the mechanical aspects such as stress and displacement were compared by finite element analysis.
Analyzed by AnSys, the observation indexes were measured as follows: for displacement of femurs, d=1.4762 (< a=3.9042 < c=3.9845 < b=4.1159) in mm is the most staple of all models; for displacement of implants (fixators or prostheses), it's similar to the behavior of femurs and with no significant difference; for stresses of femurs, no significant difference was found among all models; the stresses of implants (fixations and prostheses) were observed as d=39.6334 (< a=58.6206 < c=61.8150 < b=62.6626) in MPa correspondently, which is the least; for stresses of the general system, the average of peak values for integrated devices of all models are: d=40.8072 (< a=58.6206 < c=61.7831< b=62.6626) in MPa, which is also the least. As a final result, both maximum values for displacement and stress of mode 2 are lower than those of mode 1.
Our finite element analysis of limb salvage simulation in biomechanics proved that, to treat distal femoral bone tumors, prosthetic replacement is more efficient than intralesional curettage.
比较股骨肿瘤治疗的力学性能，以优化肢体肿瘤手术的更佳手术策略。
随机选取14例股骨CT图像，通过MIMICS重建三维模型。然后使用逆向工程软件执行模拟模式。模式1：病灶内刮除并填充骨水泥加固定器；模式2：股骨远端切除并置换肿瘤假体。最后，通过有限元分析比较应力和位移等力学方面。
通过AnSys分析，观察指标测量如下：对于股骨位移，所有模型中d = 1.4762（< a = 3.9042 < c = 3.9845 < b = 4.1159）mm是最主要的；对于植入物（固定器或假体）的位移，其与股骨的情况相似且无显著差异；对于股骨应力，所有模型之间未发现显著差异；植入物（固定器和假体）的应力分别观察为d = 39.6334（< a = 58.6206 < c = 61.8150 < b = 62.6626）MPa，这是最小的；对于整个系统的应力，所有模型的集成装置峰值平均值为：d = 40.8072（< a = 58.6206 < c = 61.7831 < b = 62.6626）MPa，这也是最小的。最终结果是，模式2的位移和应力最大值均低于模式1。
我们对肢体挽救模拟的生物力学有限元分析证明，治疗股骨远端骨肿瘤时，假体置换比病灶内刮除更有效。
