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膈神经受累性神经痛性肌萎缩(帕森尼格-特纳综合征)。

Phrenic Nerve Involvement in Neuralgic Amyotrophy (Parsonage-Turner Syndrome).

机构信息

Shirley Ryan AbilityLab, McGaw Medical Center, Northwestern University, 355 East Erie Street, 26N (Biologics), Chicago, IL 60611, USA.

Shirley Ryan AbilityLab, 355 East Erie Street, 26N (Biologics), Chicago, IL 60611, USA.

出版信息

Sleep Med Clin. 2020 Dec;15(4):539-543. doi: 10.1016/j.jsmc.2020.08.002. Epub 2020 Oct 5.

Abstract

Neuralgic amyotrophy is a poorly understood neuromuscular disorder affecting peripheral nerves mostly within the brachial plexus distribution but can also involve other sites including the phrenic nerve. In the classic form of the syndrome it causes proximal upper limb and neck pain on the affected side with subsequent muscle weakness that can be highly heterogeneous. Nocturnal noninvasive ventilation support is a first-line treatment after phrenic mononeuropathy. The regular monitoring of diaphragm function with spirometry and diaphragm ultrasound can help determine prognosis and inform decision-making.

摘要

神经痛性肌萎缩是一种发病机制尚不明确的神经肌肉疾病,主要影响臂丛分布的周围神经,但也可累及包括膈神经在内的其他部位。在该综合征的典型形式中,它会导致受累侧的近端上肢和颈部疼痛,随后出现肌肉无力,其严重程度差异较大。膈神经单神经病后,夜间无创通气支持是一线治疗方法。使用肺量计和膈超声对膈肌功能进行定期监测有助于确定预后并为决策提供信息。

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