Manappallil Robin G, Krishnan Raghuram, Veetil Pradeep P, Nambiar Harilal, Karadan Ummer, Anil Revathy, Josephine Blessy
Department of Internal Medicine, Baby Memorial Hospital, Kozhikode, Kerala, India.
Department of Cardiology, Baby Memorial Hospital, Kozhikode, Kerala, India.
Indian J Crit Care Med. 2020 Sep;24(9):882-884. doi: 10.5005/jp-journals-10071-23586.
To emphasize the importance of vitamin D supplementation.
The incidence of vitamin D deficiency has been increasing worldwide, probably due to decreased exposure to sunlight and unbalanced diet. Severe hypocalcemia following vitamin D deficiency is rather uncommon, and this leading to seizures in adults is a rare scenario.
This is the case of a 70-year-old female, a known case of coronary artery disease, who presented with one episode of seizure. Computed tomography of her brain revealed diffuse age-related atrophic changes, and electroencephalogram showed diffuse cerebral dysfunction. She was found to have severe hypocalcemia with secondary hyperparathyroidism due to vitamin D deficiency. Vitamin D bolus was given along with calcium correction, following which she improved.
There are a few reports of hypocalcemic seizures among children; however, the incidence is rare among adults. Calcium and vitamin D supplementation forms the mainstay of treatment.
Hypocalcemic seizure is uncommon, especially among adults. Vitamin D deficiency resulting in hypocalcemic seizure, to the best of our knowledge, is an unreported scenario. This case highlights the importance of vitamin D supplementation in those with reduced sunlight exposure.
Manappallil RG, Krishnan R, Veetil PP, Nambiar H, Karadan U, Anil R, Hypocalcemic Seizure Due to Vitamin D Deficiency. Indian J Crit Care Med 2020;24(9):882-884.
强调补充维生素D的重要性。
维生素D缺乏症在全球范围内的发病率一直在上升,这可能是由于阳光照射减少和饮食不均衡所致。维生素D缺乏后出现严重低钙血症相当罕见,而由此导致成人癫痫发作则是一种罕见情况。
这是一名70岁女性患者,已知患有冠状动脉疾病,出现了一次癫痫发作。她的脑部计算机断层扫描显示弥漫性与年龄相关的萎缩性改变,脑电图显示弥漫性脑功能障碍。发现她因维生素D缺乏而患有严重低钙血症并继发甲状旁腺功能亢进。给予大剂量维生素D并同时纠正钙缺乏,之后她的病情有所改善。
有一些关于儿童低钙血症性癫痫发作的报道;然而,在成人中发病率较低。补充钙和维生素D是主要治疗方法。
低钙血症性癫痫发作并不常见,尤其是在成人中。据我们所知,维生素D缺乏导致低钙血症性癫痫发作是一种未被报道的情况。该病例强调了在阳光照射减少的人群中补充维生素D的重要性。
马纳帕利尔·R·G、克里希南·R、维蒂尔·P·P、南比亚尔·H、卡拉丹·U、阿尼尔·R,《维生素D缺乏导致低钙血症性癫痫发作》。《印度危重症医学杂志》2020年;24(9):882 - 884。