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中国新冠肺炎缓解期围产期女性的心理健康结局

Mental Health Outcomes in Perinatal Women During the Remission Phase of COVID-19 in China.

作者信息

Zeng Xiaoqin, Li Wengao, Sun Hengwen, Luo Xian, Garg Samradhvi, Liu Ting, Zhang Jingying, Zhang Yongfu

机构信息

Department of Gynecology, Guangzhou Women and Children's Medical Centre, Guangzhou, China.

Department of Psychiatry, Guangdong 999 Brain Hospital, Guangzhou, China.

出版信息

Front Psychiatry. 2020 Oct 6;11:571876. doi: 10.3389/fpsyt.2020.571876. eCollection 2020.

Abstract

BACKGROUND

Since the middle of March, the COVID-19 outbreak has been well contained in China. The prevention and control measures for the outbreak have been downgraded to a normalized level. However, until now, the change in level of psychological health amongst perinatal women during the remission phase of the COVID-19 outbreak has not been investigated in China. The aim of this current study was to assess the symptoms of anxiety, depression, insomnia and quality of life (QOL) in perinatal women and to identify potential risk factors associated with these symptoms.

METHODS

This was a cross-sectional, hospital-based survey conducted between March 25 till June 5, 2020 in southern China. Convenient sampling method was adopted. Women's anxiety, depression, insomnia symptoms and QOL was examined through standardized measurements. Multivariate logistic regression and Analysis of Covariance (ANCOVA) was conducted for the same.

RESULTS

A total of 625 perinatal women completed the study; of them, 195 women (31.2%, 95%CI=27.56%-34.84%) reported anxiety, 120 (19.2%, 95%CI=16.10%-22.30%) reported depression, and 87 (13.9%, 95%CI=11.20%-16.64%) experienced symptoms of insomnia. Previous adverse experiences during pregnancy was a significant risk factor for anxiety (OR=1.628, 95%CI=1.069-2.480, P=0.023), depression (OR=1.853, 95%CI=1.153-2.977, P=0.011), and insomnia (OR=2.160, 95%CI=1.290-3.616, P=0.003). Participants having infected friends/families/colleagues were more likely to report anxiety (OR=2.195, 95%CI=1.245-3.871, P=0.007) and depression (OR=2.666, 95%CI=1.482-4.794, P=0.001). Those women whose regular check-ups were severely interrupted by the COVID-19 were also more likely to experience symptoms of anxiety (OR=2.935, 95%CI=1.701-5.062, P<0.001) and insomnia (OR=2.195, 95%CI=1.098-4.390, P=0.026).

CONCLUSION

The COVID-19 pandemic does affect the mental health and well being of perinatal women. Increased attention should be paid to women who have infected friends/families/colleagues and those with previous adverse experiences during pregnancy. Coping strategies that relieve psychological stress during the COVID-19 outbreak should be provided to prevent adverse outcomes for women and their infants.

摘要

背景

自3月中旬以来,中国的新冠疫情已得到有效控制。疫情防控措施已降至常态化水平。然而,截至目前,中国尚未对新冠疫情缓解期围产期妇女的心理健康水平变化进行调查。本研究的目的是评估围产期妇女的焦虑、抑郁、失眠症状及生活质量,并确定与这些症状相关的潜在风险因素。

方法

这是一项于2020年3月25日至6月5日在中国南方进行的基于医院的横断面调查。采用方便抽样法。通过标准化测量来检查女性的焦虑、抑郁、失眠症状及生活质量。同时进行多因素逻辑回归和协方差分析。

结果

共有625名围产期妇女完成了研究;其中,195名妇女(31.2%,95%置信区间=27.56%-34.84%)报告有焦虑症状,120名(19.2%,95%置信区间=16.10%-22.30%)报告有抑郁症状,87名(13.9%,95%置信区间=11.20%-16.64%)有失眠症状。既往孕期不良经历是焦虑(比值比=1.628,95%置信区间=1.069-2.480,P=0.023)、抑郁(比值比=1.853,95%置信区间=1.153-2.977,P=0.011)和失眠(比值比=2.160,95%置信区间=1.290-3.616,P=0.003)的重要危险因素。有感染的朋友/家人/同事的参与者更有可能报告焦虑(比值比=2.195,95%置信区间=1.245-3.871,P=0.007)和抑郁(比值比=2.666,95%置信区间=1.482-4.794,P=0.001)。那些定期产检因新冠疫情而严重中断的女性也更有可能出现焦虑症状(比值比=2.935,95%置信区间=1.701-5.062,P<0.001)和失眠(比值比=2.195,95%置信区间=1.098-4.390,P=0.026)。

结论

新冠疫情确实会影响围产期妇女的心理健康和幸福感。应更加关注有感染的朋友/家人/同事的妇女以及既往孕期有不良经历的妇女。应提供在新冠疫情期间缓解心理压力的应对策略,以防止对妇女及其婴儿产生不良后果。

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