Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, China.
Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, China.
J Affect Disord. 2022 Dec 15;319:99-111. doi: 10.1016/j.jad.2022.08.107. Epub 2022 Sep 7.
This systematic review and meta-analysis pooled the prevalence of psychological symptoms during the COVID-19 pandemic and examined the effects of the pandemic on psychological health in postpartum women.
A systematic literature search and identification were performed in PubMed, EMBASE, Web of Science, and PsycINFO databases until June 16th, 2021. The fixed or random effect models to estimate the pooled prevalence of postpartum psychological symptoms during the COVID-19 pandemic and the odds ratio (OR) of COVID-19 for psychological symptoms.
A total of 29 articles including 20,225 postpartum women during the COVID-19 pandemic and 8312 before the COVID-19 pandemic were identified. During the COVID-19 pandemic, the prevalence of postpartum depressive, anxiety, stress, and post-traumatic stress disorder symptoms were 26.7 % (95 % CI: 22.0-31.9 %), 33.8 % (95 % CI: 21.1-49.4 %), 55.0 % (95%CI: 27.9-79.5 %), and 33.7 % (95%CI: 19.6-51.5 %), respectively. The ORs of COVID-19 pandemic for postpartum depressive and anxiety symptoms were 1.54 (95 % CI: 1.00-2.36) and 2.56 (95%CI: 1.62-4.04). Subgroup analyses revealed that women with >6 weeks after delivery, younger than 35 years old, low income, less education and without breastfeeding experienced a higher risk of depressive or anxiety symptoms after delivery.
Only a few of prospective studies were included, and significant but inevitable heterogeneities were found in some analyses.
A significantly higher proportion of postpartum women were suffered from psychological symptoms during COVID-19 pandemic, particularly in those with >6 weeks after delivery, younger than 35 years old, low income, less education and formula feeding.
本系统评价和荟萃分析汇总了 COVID-19 大流行期间的心理症状发生率，并研究了大流行对产后妇女心理健康的影响。
我们在 PubMed、EMBASE、Web of Science 和 PsycINFO 数据库中进行了系统文献检索和识别，检索时间截至 2021 年 6 月 16 日。采用固定或随机效应模型来估计 COVID-19 大流行期间产后心理症状的总发生率，以及 COVID-19 与心理症状的比值比（OR）。
共纳入 29 篇文章，其中包括 COVID-19 大流行期间的 20225 名产后妇女和 COVID-19 大流行前的 8312 名产后妇女。COVID-19 大流行期间，产后抑郁、焦虑、压力和创伤后应激障碍症状的发生率分别为 26.7%（95%CI：22.0-31.9%）、33.8%（95%CI：21.1-49.4%）、55.0%（95%CI：27.9-79.5%）和 33.7%（95%CI：19.6-51.5%）。COVID-19 大流行与产后抑郁和焦虑症状的 OR 分别为 1.54（95%CI：1.00-2.36）和 2.56（95%CI：1.62-4.04）。亚组分析显示，分娩后>6 周、年龄<35 岁、收入低、教育程度低和未母乳喂养的妇女产后发生抑郁或焦虑症状的风险更高。
仅纳入了少数前瞻性研究，且一些分析中存在显著但不可避免的异质性。
COVID-19 大流行期间，产后妇女出现心理症状的比例明显更高，尤其是分娩后>6 周、年龄<35 岁、收入低、教育程度低和配方奶喂养的妇女。
