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腹腔镜尼森胃底折叠术三个月后胃食管反流病患者的生活质量

Quality of Life in Gastroesophageal Reflux Disease Three Months After Laparoscopic Nissen's Fundoplication.

作者信息

Kumar Ajay, Raja Kunal, Kumar Sumeet, Quasimuddin Nadim, Rizwan Amber

机构信息

Internal Medicine, Jinnah Sindh Medical University, Karachi, PAK.

Internal Medicine, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, PAK.

出版信息

Cureus. 2020 Sep 26;12(9):e10674. doi: 10.7759/cureus.10674.

DOI:10.7759/cureus.10674
PMID:33133840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7592527/
Abstract

INTRODUCTION

Gastroesophageal reflux disease (GERD) affects various elements of life including sleep, daily and social functioning, and physical and emotional activities. This study aims to determine the impact of laparoscopic Nissen's fundoplication (LNF) on health-related quality of life.

METHODS

This prospective study was conducted in a tertiary care hospital, Pakistan, from Jan 2019 to Feb 2020. Forty-seven participants completed the study. All patients completed the Gastroesophageal Reflux Disease Health-Related Quality of Life (GERD-HRQoL) questionnaire both pre-operatively and three months after LNF.

RESULTS

There was significant difference in pre- and post-operative median Health-Related Quality of Life score (p value: 0.0073). There was improvement in items related to heartburn in HRQoL questionnaire, while questions related to swallowing and bloating either showed no change or worsening.

CONCLUSION

LNF has a significant impact on health-related quality of life. It is important for the physician to consider the impact of GERD in daily life. Management goals for GERD should also include improvement in quality of life of the patient.

摘要

引言

胃食管反流病（GERD）会影响生活的各个方面，包括睡眠、日常和社交功能以及身体和情感活动。本研究旨在确定腹腔镜尼氏胃底折叠术（LNF）对健康相关生活质量的影响。

方法

这项前瞻性研究于2019年1月至2020年2月在巴基斯坦的一家三级护理医院进行。47名参与者完成了该研究。所有患者在术前和LNF术后三个月均完成了胃食管反流病健康相关生活质量（GERD-HRQoL）问卷。

结果

术前和术后的健康相关生活质量中位数得分存在显著差异（p值：0.0073）。HRQoL问卷中与烧心相关的项目有所改善，而与吞咽和腹胀相关的问题要么没有变化，要么有所恶化。

结论

LNF对健康相关生活质量有显著影响。医生考虑GERD对日常生活的影响很重要。GERD的管理目标还应包括改善患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df59/7592527/e0b8499cff40/cureus-0012-00000010674-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df59/7592527/e0b8499cff40/cureus-0012-00000010674-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df59/7592527/e0b8499cff40/cureus-0012-00000010674-i01.jpg

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J Pak Med Assoc. 2014 Jul;64(7):751-7.
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Quality of life following laparoscopic Nissen fundoplication: assessing short-term and long-term outcomes.腹腔镜胃底折叠术（Nissen fundoplication）后生活质量：评估短期和长期结果。
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胃食管反流病：老年患者的重要考量因素
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Persistent reflux symptoms in the proton pump inhibitor era: the changing face of gastroesophageal reflux disease.质子泵抑制剂时代的持续性反流症状：胃食管反流病的面貌变迁
Gastroenterology. 2010 Jul;139(1):7-13.e3. doi: 10.1053/j.gastro.2010.05.016. Epub 2010 May 20.
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Quality of life and patient satisfaction 3 months and 3 years after laparoscopic Nissen's fundoplication.腹腔镜尼氏胃底折叠术3个月及3年后的生活质量和患者满意度
Saudi J Gastroenterol. 2008 Jan;14(1):24-7. doi: 10.4103/1319-3767.37799.
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The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus.《蒙特利尔胃食管反流病的定义与分类：一项全球循证共识》
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