Cristiano L, Lorenzi M
Laboratorio di analisi chimico-cliniche e microbiologiche, Ospedale Briolini, U.S.S.L. 26, Gazzaniga, Bergamo.
Quad Sclavo Diagn. 1986 Dec;22(4):398-411.
328 samples of vaginal discharges in adult fertile women, aged between 16 and 48, were examined in this trial. After excluding 95 women (39 were affected by vaginal Trichomoniasis, 55 whose discharge presented yeasts and 1 affected by gonococcal infection), the authors divided the remaining 233 cases into subjects affected or not affected by nonspecific vaginitis (NSV) only using a Gram-stained smear. In the 83 patients affected by NSV, the authors isolated Gardnerella vaginalis in the 90.4% of the cases. After statistically correlating the different parameters described in literature as associated to NSV (pH, KOH-test, Clue Cells, isolation of G. vaginalis, symptoms), the authors concluded that: a) Gram-stained smear may be used as a simple microscopical test for diagnosis, in most of the cases, NSV; b) in most of the cases of NSV are implicated more organisms (essentially G. vaginalis and anaerobic organisms); c) G. vaginalis can be considered as a marker of these infections.
在本次试验中，对年龄在16至48岁之间的328例成年育龄女性的阴道分泌物样本进行了检查。在排除95名女性（39名患有阴道毛滴虫病，55名分泌物中有酵母菌，1名患有淋球菌感染）后，作者仅使用革兰氏染色涂片将其余233例病例分为受非特异性阴道炎（NSV）影响或未受影响的受试者。在83例受NSV影响的患者中，作者在90.4%的病例中分离出阴道加德纳菌。在对文献中描述的与NSV相关的不同参数（pH值、氢氧化钾试验、线索细胞、阴道加德纳菌的分离、症状）进行统计学关联后，作者得出以下结论：a）革兰氏染色涂片在大多数情况下可作为诊断NSV的简单显微镜检查方法；b）在大多数NSV病例中，涉及多种微生物（主要是阴道加德纳菌和厌氧菌）；c）阴道加德纳菌可被视为这些感染的标志物。
