Luna M A, Batsakis J G, Ordóñez N G, Mackay B, Tortoledo M E
University of Texas System Cancer Center, Department of Pathology, M. D. Anderson Hospital and Tumor Institute, Houston 77030.
Semin Diagn Pathol. 1987 May;4(2):117-35.
Myoepithelial cells play an important role in the histogenesis of adenocarcinomas arising from the salivary duct unit nearest the acini. Prototype adenocarcinomas arising from the intercalated duct are the terminal duct carcinoma and the epimyoepithelial carcinoma, both typically low-grade malignancies. Those salivary adenocarcinomas arising from the larger nonintercalated excretory ducts do not manifest myoepithelial cells in their composition. A prime example is the salivary duct carcinoma, which is a high-grade malignancy. These adenocarcinomas have distinctive clinical and pathologic features and they should be recognized by the examining pathologist. Because of the potential clinical confusion between terminal duct carcinoma and salivary duct carcinoma when rendered as a diagnosis, each should be further qualified, eg, by adding high or low grade.
肌上皮细胞在起源于最靠近腺泡的唾液腺导管单位的腺癌组织发生中起重要作用。起源于闰管的典型腺癌是终末导管癌和肌上皮癌，两者通常都是低级别恶性肿瘤。那些起源于较大的非闰管排泄导管的唾液腺癌在其组成中不显示肌上皮细胞。一个主要例子是唾液导管癌，它是一种高级别恶性肿瘤。这些腺癌具有独特的临床和病理特征，检查病理学家应予以识别。由于终末导管癌和唾液导管癌在诊断时可能存在临床混淆，因此每种都应进一步限定，例如，通过添加高或低级别。
