IRCCS Istituto Ortopedico Galeazzi, Italy.
NeuroRehabilitation. 2020;47(4):509-511. doi: 10.3233/NRE-209008.
Epidural corticosteroid injection is one of the most common non-surgical procedures for lumbosacral radicular pain.
To assess efficacy and safety of epidural corticosteroid injections compared with placebo injections in patients with lumbosacral radicular pain.
A summary and commentary of a Cochrane Review by Oliveira et al.RESULTS:25 studies with a total of 2740 participants were included in the review. Moderate quality evidence pointed out a small effect on leg pain at immediate and short-term follow-up and on disability at short-term and intermediate follow-up. Adverse events were not different between corticosteroid and placebo injections.
Epidural corticosteroid injection is slightly more effective than placebo for leg pain and disability at short-term follow up. Clinicians and patients however should be informed of the small effect size of the treatment.
硬膜外皮质类固醇注射是治疗腰骶神经根痛最常见的非手术方法之一。
评估与安慰剂注射相比，硬膜外皮质类固醇注射治疗腰骶神经根痛患者的疗效和安全性。
对 Oliveira 等人进行的 Cochrane 综述的总结和评论。
该综述共纳入 25 项研究，共计 2740 名参与者。中等质量证据表明，在即时和短期随访时对腿部疼痛以及在短期和中期随访时对残疾有较小的影响。皮质类固醇和安慰剂注射的不良事件无差异。
在短期随访时，硬膜外皮质类固醇注射比安慰剂对腿部疼痛和残疾的疗效稍好。然而，临床医生和患者应该了解治疗的效果大小较小。
