Brochhausen Mathias, Empey Philip E, Schneider Jodi, Hogan William R, Boyce Richard D
Department of Biomedical Infonnatics, University of Arkansas for Medical Sciences, Little Rock, AR USA.
Department of Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA USA.
CEUR Workshop Proc. 2016 Aug;1747.
In this poster we present novel development and extension of the Drug-drug Interaction and Drug-drug Interaction Evidence Ontology (DIDEO). We demonstrate how reasoning over this extension of DIDEO can a) automatically create a multi-level hierarchy of evidence types from descriptions of the underlying scientific observations and b) automatically subsume individual evidence items under the correct evidence type. Thus DIDEO will enable evidence items added manually by curators to be automatically categorized into a drug-drug interaction framework with precision and minimal effort from curators. As with all previous DIDEO development this extension is consistent with OBO Foundry principles.
在本海报中，我们展示了药物相互作用及药物相互作用证据本体（DIDEO）的新进展和扩展。我们展示了基于DIDEO的这种扩展进行推理如何能够：a）根据基础科学观察的描述自动创建证据类型的多层次层次结构，以及b）将各个证据项自动归入正确的证据类型之下。因此，DIDEO将使策展人手动添加的证据项能够自动、精确地归类到药物相互作用框架中，且策展人只需付出最少的努力。与之前所有的DIDEO开发一样，此扩展符合OBO铸造厂原则。
