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小儿耳鼻喉科门诊收治的新生儿和婴儿吸气性喘鸣:诊断方法和治疗结果。

Inspiratory stridor of newborns and infants admitted to a paediatric ENT outpatient clinic: diagnostic approach and therapeutic outcome.

机构信息

Paediatric Otorhinolaryngology, Head and Neck Surgery Department, La Timone Children's Hospital, Aix-Marseille University, 264 rue Saint Pierre, 13385, Marseille Cedex 5, France.

Otorhinolaryngology, Head and Neck Surgery Department, CHU Clermont-Ferrand, Université Clermont Auvergne, Clermont-Ferrand, France.

出版信息

Eur J Pediatr. 2021 Apr;180(4):1177-1183. doi: 10.1007/s00431-020-03858-3. Epub 2020 Nov 2.

Abstract

The main objective was to analyse the use of rigid laryngotracheoscopy under general anaesthesia (GA) and endoscopic surgery in the management of inspiratory stridor in patients referred to a paediatric ENT outpatient clinic. The secondary objective was to analyse the aetiological diagnoses made and their therapeutic management. This is a prospective study including all newborns and infants, corresponding to 190 patients, presenting for the first time in consultation for inspiratory stridor from January 2015 to December 2017. A consultation form was filled out after each consultation and added to a database; a management algorithm was used to determine which patients required a rigid laryngotracheoscopy. A 17.9% (n = 34) of the patients required rigid laryngotracheoscopy, of whom 12.6% (n = 24) underwent concomitant endoscopic surgery. A 65.8% (n = 125) of the patients were diagnosed with laryngomalacia, 21.1% (n = 40) with isolated posterior excess of mucosa, 9.5% (n = 18) with another diagnosis and 3.7% (n = 7) with a normal examination. The presence of comorbidity was associated (p < 0.001) with the use of rigid laryngotracheoscopy and endoscopic surgery.Conclusion: Rigid laryngotracheoscopy under GA was required in one in five to six patients. Conservative management with strict follow-up may be appropriate in a large number of patients, especially those with laryngomalacia. What is Known: • Previous research has established that laryngomalacia is the main aetiology of stridor. • Comorbidities are linked with a poor tolerance of stridor. What is new: • About one in five to six patients seen in consultation for stridor will require a trip to the operative room (and one in eight will require endoscopic surgery). • Laryngomalacia and isolated posterior excess of mucosa account for 85-90% of the patients seen in consultation for stridor.

摘要

目的

分析全麻下硬性气管镜检查和内镜手术在小儿耳鼻喉科门诊治疗吸气性喘鸣患者中的应用。次要目的:分析病因诊断及其治疗管理。这是一项前瞻性研究,纳入 2015 年 1 月至 2017 年 12 月首次因吸气性喘鸣就诊的所有新生儿和婴儿共 190 例患者。每次就诊后填写咨询表并添加到数据库中;使用管理算法来确定哪些患者需要硬性气管镜检查。17.9%(n=34)的患者需要硬性气管镜检查,其中 12.6%(n=24)同时进行内镜手术。65.8%(n=125)的患者被诊断为喉软骨软化,21.1%(n=40)为单纯后黏膜过剩,9.5%(n=18)为其他诊断,3.7%(n=7)为正常检查。合并症的存在与硬性气管镜检查和内镜手术的应用相关(p<0.001)。结论:全麻下硬性气管镜检查在五分之一至六分之一的患者中是必需的。在大量患者中,尤其是喉软骨软化患者,采用保守治疗并严格随访可能是合适的。已知:• 先前的研究已经确定喉软骨软化是喘鸣的主要病因。• 合并症与喘鸣的耐受性差有关。新发现:• 在因喘鸣就诊的患者中,约五分之一至六分之一需要进入手术室(八分之一需要内镜手术)。• 在因喘鸣就诊的患者中,喉软骨软化和单纯后黏膜过剩占 85-90%。

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