Division of Pediatric Pulmonology, School of Medicine, Marmara University, Istanbul, Turkey.
Eur Arch Otorhinolaryngol. 2013 Jan;270(1):21-5. doi: 10.1007/s00405-012-2057-9. Epub 2012 May 26.
The aim is to determine clinical characteristics, flexible bronchoscopy (FB) findings including associated airway abnormalities and other conditions, treatment modalities and long term follow-up of children with congenital stridor. Medical records of children, who underwent FB for the evaluation of stridor between 1 January 2004 and 31 December 2009 were retrospectively reviewed. Demographic characteristics, symptoms and physical examination findings at presentation, FB findings, follow-up data including the time to resolution of symptoms and treatment modalities, presence of associated conditions were assessed. 109 children were enrolled to the study. Laryngomalacia was the most common etiology for stridor. Laryngomalacia was isolated in 37 patients and 54 patients had secondary airway lesions (SALs). Diagnoses other than laryngomalacia such as subglottic hemangioma, subglottic web, isolated tracheomalacia were found in 18 patients. In 90 % of patients, stridor resolved before 3 years of age without any surgical intervention and there was no significant difference in terms of the persistence of stridor between patients with isolated laryngomalacia and associated SALs. Duration of stridor was significantly longer in both patients with neurological abnormalities and reflux symptoms. Surgical procedure was performed in 19 of the patients. There is a high incidence of SALs in patients with laryngomalacia. FB is helpful for identifying anomalies requiring surgical treatment.
目的在于确定先天性喘鸣患儿的临床特征、纤维支气管镜(FB)检查结果(包括相关气道异常和其他情况)、治疗方式以及长期随访情况。回顾性分析 2004 年 1 月 1 日至 2009 年 12 月 31 日期间因喘鸣接受 FB 检查的患儿的病历资料。评估人口统计学特征、就诊时的症状和体格检查结果、FB 检查结果、包括症状缓解时间和治疗方式的随访数据以及是否存在相关疾病。共纳入 109 例患儿。喉软化是喘鸣的最常见病因。37 例患儿为孤立性喉软化,54 例患儿存在继发性气道病变(SAL)。18 例患儿的诊断除喉软化以外,还包括声门下血管瘤、声门下蹼、孤立性气管软化。90%的患儿在 3 岁前无需手术干预即可缓解喘鸣,孤立性喉软化和伴有 SAL 的患儿喘鸣持续时间无显著差异。伴有神经异常和反流症状的患儿喘鸣持续时间明显更长。19 例患儿接受了手术治疗。喉软化患儿 SAL 发生率较高。FB 有助于发现需要手术治疗的异常。