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COVID-19 患者病情突然恶化和 SARS COV-2 病毒在肺部的扩散。

Abrupt Deterioration of COVID-19 Patients and Spreading of SARS COV-2 Virions in the Lungs.

机构信息

Faculty of Engineering, University of Kragujevac, Sestre Janjic 6, 34000, Kragujevac, Serbia.

Biomedical Research and Development Center for Bioengineering (BIOIRC), Prvoslava Stojanovica 6, 34000, Kragujevac, Serbia.

出版信息

Ann Biomed Eng. 2020 Dec;48(12):2705-2706. doi: 10.1007/s10439-020-02676-w. Epub 2020 Nov 2.

DOI:10.1007/s10439-020-02676-w
PMID:33140243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7605482/
Abstract

A unique feature of COVID-19 interstitial pneumonia is an abrupt progression to respiratory failure. Our calculation shows that this abrupt deteriorate may be caused by a sudden shift in the spread of virus-laden bioaerosols through the airways to many different regions of the lungs from the initial site of infection.

摘要

COVID-19 间质性肺炎的一个独特特征是迅速进展为呼吸衰竭。我们的计算表明，这种急剧恶化可能是由于病毒载量的生物气溶胶通过呼吸道向肺部的许多不同区域传播的突然转变，而不是从初始感染部位开始。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8524/7605482/bf29151b36a4/10439_2020_2676_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8524/7605482/bf29151b36a4/10439_2020_2676_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8524/7605482/bf29151b36a4/10439_2020_2676_Fig1_HTML.jpg

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