Hu Ju Long, Yoo Hyokyung, Kwon Sung Tack, Kim Sukwha, Chung Jee Hyeok, Kim Hyeonwoo, Kim Jinhyun, Yu Na Hee, Kim Byung Jun
Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Biomedical Research Institute, Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul, Korea.
Arch Craniofac Surg. 2020 Oct;21(5):288-293. doi: 10.7181/acfs.2020.00528. Epub 2020 Oct 20.
Pilomatrixoma is a benign tumor that originates from the hair follicle matrix. It usually presents as a hard, slow growing, solitary mass that can be easily misdiagnosed as other skin masses. The aim of this study was to clinically analyze a case series of pilomatrixoma in pediatric patients from Korea.
A total of 165 pediatric patients from 2011 to 2018 with a histological diagnosis of pilomatrixoma were included. A retrospective review was performed using the electronic medical records, including patient demographics, number and location of the mass, clinical and imaging presentation, and postoperative outcomes.
There were 61 male and 104 female patients with 152 solitary and 13 multiple pilomatrixomas. Among solitary pilomatrixomas, the lesion commonly occurred in the head and neck (84.2%), followed by upper limbs (11.2%), lower limbs (3.3%), and trunk (1.3%). The pilomatrixoma lesion presented as the following types based on our clinical classification: mass (56.02%), pigmentation (25.31%), mixed (12.65%), ulceration (4.82%), and keloid-like (1.2%). Ultrasonography showed a high positive predictive value (95.56%). There were no specific complications observed except for two cases of recurrence.
Pilomatrixoma has various clinical feature presentations and commonly occurs in the head and neck. Ultrasonography is a helpful diagnostic tool. Surgical removal of the lesion is the main treatment method with a low recurrence rate.
毛发上皮瘤是一种起源于毛囊基质的良性肿瘤。它通常表现为质地坚硬、生长缓慢的孤立性肿块，很容易被误诊为其他皮肤肿块。本研究的目的是对韩国儿科患者的一系列毛发上皮瘤病例进行临床分析。
纳入2011年至2018年共165例经组织学诊断为毛发上皮瘤的儿科患者。使用电子病历进行回顾性分析，包括患者人口统计学资料、肿块数量和位置、临床及影像学表现以及术后结果。
有61例男性和104例女性患者，共152个孤立性毛发上皮瘤和13个多发性毛发上皮瘤。在孤立性毛发上皮瘤中，病变常见于头颈部（84.2%），其次是上肢（11.2%）、下肢（3.3%）和躯干（1.3%）。根据我们的临床分类，毛发上皮瘤病变表现为以下类型：肿块型（56.02%）、色素沉着型（25.31%）、混合型（12.65%）、溃疡型（4.82%）和瘢痕疙瘩样型（1.2%）。超声检查显示出较高的阳性预测价值（95.56%）。除2例复发外，未观察到其他特定并发症。
毛发上皮瘤有多种临床特征表现，常见于头颈部。超声检查是一种有用的诊断工具。手术切除病变是主要治疗方法，复发率较低。
