Department of Dermatology, Korea University Guro Hospital, Seoul, Korea.
Derpartment of Pathology, Korea University Guro Hospital, Seoul, Korea.
Int J Dermatol. 2017 Oct;56(10):1032-1036. doi: 10.1111/ijd.13732.
Clinically, pilomatricoma offers potential for a wide spectrum of differential diagnoses. It typically occurs in pediatric patients with the head being the most common location. A second peak of clinical presentation occurs in adults at age 50-65 years, suggesting a bimodal pattern of occurrence.
To investigate the clinical and epidemiological features of pilomatricoma in adults over 20 years old, as it is a common and frequently misdiagnosed tumor.
This was a retrospective study of pilomatricomas surgically removed at a tertiary hospital between January 1994 and December 2014. A search of the all-pathological database of patients aged over 20 years old with a pathological diagnosis of pilomatricoma was carried out.
The clinical preoperative diagnosis of pilomatricoma was made in 34.0% of cases. Tumor location showed a predilection to the head and neck. Of the reported concomitant neoplasm, a majority had accompanying skin tumors.
We conclude that clinical features in adults were similar to those of children. This study outlines clinical presentations that should help to guide differential diagnoses. Additionally, because of similarities between the distribution and depth of vellus hair follicles and pilomatricomas, it is probable that vellus hair bulbs may be the origin of this tumor.
临床上，毛母质瘤具有广泛的鉴别诊断潜力。它通常发生在头部是最常见部位的儿科患者中。第二个发病高峰出现在 50-65 岁的成年人中，表明存在双峰发病模式。
研究 20 岁以上成年人毛母质瘤的临床和流行病学特征，因为它是一种常见且经常误诊的肿瘤。
这是一项对 1994 年 1 月至 2014 年 12 月在一家三级医院通过手术切除的毛母质瘤进行的回顾性研究。对所有年龄在 20 岁以上、病理诊断为毛母质瘤的患者的病理数据库进行了搜索。
术前临床诊断为毛母质瘤的比例为 34.0%。肿瘤位置偏向头颈部。报告的伴发肿瘤中，大多数伴有皮肤肿瘤。
我们得出结论，成年人的临床特征与儿童相似。本研究概述了有助于指导鉴别诊断的临床表现。此外，由于毳毛毛囊的分布和深度与毛母质瘤相似，因此毛球可能是这种肿瘤的起源。
