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2019冠状病毒病肺炎患者行长期机械通气时经皮气管切开术的安全性及预后

Safety and outcomes of percutaneous tracheostomy in coronavirus disease 2019 pneumonitis patients requiring prolonged mechanical ventilation.

作者信息

Takhar A, Tornari C, Amin N, Wyncoll D, Tricklebank S, Arora A, Ahmad I, Simo R, Surda P

机构信息

Department of Otolaryngology and Head and Neck Surgery, Guy's and St Thomas' NHS Foundation Trust, King's College London, London, UK.

Department of Critical Care, Guy's and St Thomas' NHS Foundation Trust, King's College London, London, UK.

出版信息

J Laryngol Otol. 2020 Nov 4:1-10. doi: 10.1017/S0022215120002303.

Abstract

OBJECTIVES

Tracheostomy for coronavirus disease 2019 pneumonitis patients requiring prolonged invasive mechanical ventilation remains a matter of debate. This study analysed the timing and outcomes of percutaneous tracheostomy, and reports our experience of a dedicated ENT-anaesthetics department led tracheostomy team.

METHOD

A prospective single-centre observational study was conducted of patients undergoing tracheostomy, who had been diagnosed with coronavirus disease 2019 pneumonitis, between 21st March and 20th May 2020.

RESULTS

Eighty-one patients underwent tracheostomy after a median (interquartile range) of 16 (13-20) days of invasive mechanical ventilation. Median follow-up duration was 32 (23-40) days. Of patients, 86.7 per cent were successfully liberated from invasive mechanical ventilation in a median (interquartile range) of 12 (7-16) days. Moreover, 68.7 per cent were subsequently discharged from hospital. On univariate analysis, there was no difference in outcomes between early (before day 14) and late (day 14 or later) tracheostomy. The mortality rate was 8.6 per cent and no deaths were tracheostomy related.

CONCLUSION

Outcomes appear favourable when patients are carefully selected. Percutaneous tracheostomy performed via a multidisciplinary approach, with appropriate training, was safe and optimised healthcare resource utilisation.

摘要

目的

对于需要长期有创机械通气的2019冠状病毒病肺炎患者,气管切开术仍存在争议。本研究分析了经皮气管切开术的时机和结果,并报告了我们在一个由耳鼻喉科-麻醉科主导的专门气管切开术团队的经验。

方法

对2020年3月21日至5月20日期间接受气管切开术且被诊断为2019冠状病毒病肺炎的患者进行了一项前瞻性单中心观察性研究。

结果

81例患者在有创机械通气中位(四分位间距)16(13 - 20)天后接受了气管切开术。中位随访时间为32(23 - 40)天。在中位(四分位间距)12(7 - 16)天内,86.7%的患者成功脱离有创机械通气。此外,68.7%的患者随后出院。单因素分析显示,早期(第14天之前)和晚期(第14天或之后)气管切开术的结果没有差异。死亡率为8.6%,且没有死亡与气管切开术相关。

结论

经过精心挑选患者,结果似乎良好。通过多学科方法进行经皮气管切开术,并经过适当培训,是安全的且优化了医疗资源利用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a4a/7729174/a403b18b3174/S0022215120002303_fig1.jpg

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