Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Ann Thorac Surg. 2021 Aug;112(2):564-571. doi: 10.1016/j.athoracsur.2020.09.023. Epub 2020 Nov 2.
Minimally invasive aortic valve replacement through anterior right thoracotomy (ART) has shown to be safe and feasible. However, acceptance within the surgical community is low. Rapid-deployment aortic valves may be a game changer due to simplified surgical technique and shorter operative times. Therefore, the combination of advanced surgical techniques like the ART access with rapid-deployment aortic valves was assessed in this study.
We retrospectively analyzed all patients undergoing ART with the Edwards Intuity Elite (Edwards Lifesciences, Irvine, CA) valve system between 2011 and 2018. Patient data were collected prospectively in an ongoing, single-center registry. Data analysis regarding valve outcome was performed according to current guidelines.
In all, 165 patients underwent aortic valve replacement through ART access with the Edwards Intuity valve system (age 73 ± 9 years, 49% female, median European System for Cardiac Operative Risk Evaluation II score 1.6 [range, 0.6 to 10.6]). Median cardiopulmonary bypass time was 114 minutes (range, 61 to 310) and median aortic cross-clamp time was 80 minutes (range, 45 to 230). Thirty-day as well as inhospital mortality was 0.6% (n = 1). Postoperative neurologic events occurred in 3%, resulting in major neurologic deficit in 1 patient. Intermediate and long-term survival was 99%, 98%, and 93% after 6 months, 1 year, and 3 years, respectively.
Implantation of the Edwards Intuity valve system through ART is safe, feasible, and reproducible. The overall results of this single center experience are excellent compared with contemporary series of both surgical and transcatheter aortic valve replacements.
经前右胸切开微创主动脉瓣置换术 (ART) 已被证明是安全且可行的。然而,该手术在外科界的接受程度较低。由于手术技术简化和手术时间缩短,快速部署主动脉瓣可能会改变游戏规则。因此,本研究评估了先进的外科技术(如 ART 入路)与快速部署主动脉瓣的结合。
我们回顾性分析了 2011 年至 2018 年间所有接受经前右胸切开术并用 Edwards Intuity Elite(爱德华生命科学公司,加利福尼亚州欧文)瓣膜系统进行主动脉瓣置换术的患者。患者数据在一个正在进行的单中心登记处前瞻性收集。根据现行指南对瓣膜结果进行数据分析。
共有 165 例患者接受了经前右胸切开术并用 Edwards Intuity 瓣膜系统进行主动脉瓣置换术(年龄 73 ± 9 岁,49%为女性,中位欧洲心脏手术风险评估系统 II 评分 1.6 [范围 0.6 至 10.6])。中位体外循环时间为 114 分钟(范围 61 至 310),中位主动脉阻断时间为 80 分钟(范围 45 至 230)。30 天和住院死亡率为 0.6%(n=1)。术后神经系统事件发生率为 3%,导致 1 例患者出现严重神经系统缺陷。术后 6 个月、1 年和 3 年的中期和长期生存率分别为 99%、98%和 93%。
通过 ART 植入 Edwards Intuity 瓣膜系统是安全、可行且可重复的。与同期的外科和经导管主动脉瓣置换术系列相比,本单中心经验的总体结果非常出色。