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80 岁以上老年患者的直肠癌手术:行 Hartmann 手术安全吗?

Rectal Cancer Surgery in Patients Older Than 80 Years: Is Hartmann's Procedure Safe?

机构信息

Department of Surgery, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan

Department of Surgery, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.

出版信息

In Vivo. 2020 Nov-Dec;34(6):3661-3667. doi: 10.21873/invivo.12213.

DOI:10.21873/invivo.12213
PMID:33144482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7811640/
Abstract

BACKGROUND/AIM: The current study aimed to identify the safety and efficacy of Hartmann's procedure (HP) among elderly patients (age ≥80 years) with rectal cancer.

PATIENTS AND METHODS

Data on surgical outcome, survival rate, and incidence of stoma reversal were retrospectively compared between patients aged over 80 years who underwent anterior resection (AR) and HP.

RESULTS

In total, 79 elderly patients underwent rectal cancer surgery. Of these patients, 54 (68.4%) underwent AR and 25 (31.6%) HP. The two groups did not differ significantly in terms of age, nutrient status, and tumor characteristics. Eight (14.8%) patients who underwent AR and six (24.0%) who underwent HP presented with intra-abdominal complications (p=0.35). The overall survival and recurrent-free survival rates between the two groups did not differ.

CONCLUSION

HP for elderly patients with rectal cancer has similar complication rates to AR, and achieved similar oncological outcomes.

摘要

背景/目的:本研究旨在确定高龄(≥80 岁)直肠癌患者行Hartmann 手术(HP)的安全性和有效性。

患者和方法

回顾性比较了年龄>80 岁行直肠前切除术(AR)和 HP 的患者的手术结果、生存率和造口逆转发生率。

结果

共 79 例老年直肠癌患者接受手术治疗。其中 54 例(68.4%)行 AR,25 例(31.6%)行 HP。两组在年龄、营养状况和肿瘤特征方面无显著差异。行 AR 的 8 例(14.8%)和行 HP 的 6 例(24.0%)患者出现腹腔内并发症(p=0.35)。两组的总生存率和无复发生存率无差异。

结论

HP 治疗高龄直肠癌患者的并发症发生率与 AR 相似,且具有相似的肿瘤学疗效。

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本文引用的文献

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The 2019 WHO classification of tumours of the digestive system.2019年世界卫生组织消化系统肿瘤分类。
Histopathology. 2020 Jan;76(2):182-188. doi: 10.1111/his.13975. Epub 2019 Nov 13.
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Population-based cohort study of the impact on postoperative mortality of anastomotic leakage after anterior resection for rectal cancer.基于人群的队列研究:直肠癌前切除术后吻合口漏对术后死亡率的影响。
BJS Open. 2018 Oct 15;3(1):106-111. doi: 10.1002/bjs5.50106. eCollection 2019 Feb.
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Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer.老年直肠癌患者的个体化管理:欧洲外科肿瘤学会、欧洲结直肠外科学会、国际老年肿瘤学会和美国外科医师学会癌症委员会的专家建议。
Eur J Surg Oncol. 2018 Nov;44(11):1685-1702. doi: 10.1016/j.ejso.2018.08.003. Epub 2018 Aug 15.
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Low Hartmann's procedure or intersphincteric proctectomy for distal rectal cancer: a retrospective comparative cohort study.低位哈特曼手术或括约肌间直肠切除术治疗低位直肠癌:一项回顾性比较队列研究。
Int J Colorectal Dis. 2017 Nov;32(11):1583-1589. doi: 10.1007/s00384-017-2886-5. Epub 2017 Aug 11.
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Hartmann's procedure vs abdominoperineal resection with intersphincteric dissection in patients with rectal cancer: a randomized multicentre trial (HAPIrect).直肠癌患者Hartmann手术与经括约肌间分离的腹会阴联合切除术对比:一项随机多中心试验(HAPIrect)
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7
Outcomes with multimodal therapy for elderly patients with rectal cancer.老年直肠癌患者的多模式治疗结果。
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8
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Complications and risk prediction in treatment of elderly patients with rectal cancer.老年直肠癌患者治疗中的并发症与风险预测
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