Karligkiotis Apostolos, Bozkurt Gülpembe, Pietrobon Giacomo, Battaglia Paolo, Turri-Zanoni Mario, Chu Francesco, Ansarin Mohssen, Ottini Giorgia, De Luca Marco, Uccella Silvia, Castelnuovo Paolo
Division of Otorhinolaryngology, Department of Surgical Specialties, ASST Sette Laghi, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria-Varese, ASST Sette Laghi, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Turk Arch Otorhinolaryngol. 2020 Sep;58(3):186-192. doi: 10.5152/tao.2020.5382. Epub 2020 Sep 1.
The aim of this study is to describe the clinicopathological characteristics of intranasal pleomorphic adenomas (PAs), as well as the role and outcomes of endoscopic endonasal resection. A retrospective review of the clinical data from patients with PA of the nasal cavity who were treated by the authors at three tertiary medical centers between June 1998 and December 2019. A total of five patients with PA were found. Three patients were male, two were female and their mean age was 62.2 years. All cases were resected "en bloc" with endoscopic endonasal approach. No evidence of disease was observed during a mean follow-up of 10.6 years. No case presented with malignant transformation into carcinoma ex-PA. PA of the sinonasal tract and the nasopharynx is difficult to diagnose due to nonspecific clinical and radiological findings. Endoscopic endonasal approaches can be considered the gold standard in the treatment of these tumors and provide excellent visual control of the surgical field and clear margins.
本研究的目的是描述鼻内多形性腺瘤（PAs）的临床病理特征，以及鼻内镜下经鼻切除术的作用和结果。回顾性分析1998年6月至2019年12月期间作者在三个三级医疗中心治疗的鼻腔多形性腺瘤患者的临床资料。共发现5例多形性腺瘤患者。3例为男性，2例为女性，平均年龄为62.2岁。所有病例均采用鼻内镜下经鼻入路“整块”切除。平均随访10.6年期间未观察到疾病复发迹象。无病例出现多形性腺瘤恶变形成癌。由于临床和影像学表现不具有特异性，鼻窦和鼻咽部的多形性腺瘤难以诊断。鼻内镜下经鼻入路可被视为治疗这些肿瘤的金标准，能提供良好的手术视野可视化和清晰的切缘。
