University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
University Clinical Center of Vojvodina, Department of Otorhinolaryngology and Head and Neck Surgery, Novi Sad, Serbia.
Acta Clin Croat. 2023 Aug;62(2):387-390. doi: 10.20471/acc.2023.62.02.20.
Pleomorphic adenoma is very rare in the sinonasal region, with the most common localization on the nasal septum, followed by lateral nasal wall. In the case presented, a 72-year-old woman was complaining of the right sided nasal obstruction without any other symptoms. The symptom started a year before and increased progressively. Anterior rhinoscopy revealed a mucosa-covered, smooth-surfaced, soft, polypoid, pale, grayish-pink in color mass in the right nasal cavity, approximately 2x2 cm in size. Nasal endoscopy showed the mass to have a broad base on the lateral nasal wall. Computerized tomography scan showed a homogeneous, solid soft tissue mass, 25x18x12 mm in size, which was attached to the lateral nasal wall, behind the nasal vestibule, just in front of the inferior turbinate. Endonasal endoscopic complete tumor excision was performed, during which some spillage of the tumor occurred. Histology diagnosis was pleomorphic adenoma of minor salivary glands. The patient was followed up on regular basis and had no tumor recurrence in the 6 postoperative year. Intranasal pleomorphic adenoma arising from the lateral nasal wall in front of the inferior turbinate is extremely rare, so the presented case is probably the first ever published.
多形性腺瘤在鼻腔鼻窦中非常罕见,最常见的部位是鼻中隔,其次是外侧鼻壁。在本例中,一名 72 岁女性因右侧鼻塞而就诊,无其他任何症状。该症状始于一年前,并逐渐加重。前鼻镜检查显示右侧鼻腔内有一个被黏膜覆盖的、表面光滑、柔软、息肉样、苍白、略带灰色的粉红色肿块,大小约为 2x2cm。鼻内窥镜检查显示肿块在外侧鼻壁上有一个宽阔的基底。计算机断层扫描显示一个大小为 25x18x12mm 的均匀实性软组织肿块,附着于外侧鼻壁,位于鼻前庭后面,下鼻甲前面。进行了经鼻内镜下完整肿瘤切除术,在此过程中肿瘤有一些溢出。组织学诊断为小唾液腺多形性腺瘤。患者定期随访,术后 6 年无肿瘤复发。发生在下鼻甲前方外侧鼻壁的鼻腔内多形性腺瘤极为罕见,因此本例可能是首例报道。