Siniorakis Eftychios, Arvanitakis Spyridon, Elkouris Maximilianos
Department of Cardiology, Sotiria Chest Diseases Hospital, 152 Mesogeion Avenue, 11527, Athens, Greece.
Department of Clinical Biochemistry, Sotiria Chest Diseases Hospital, 152 Mesogeion Avenue, 11527, Athens, Greece.
An Acad Bras Cienc. 2020 Oct 28;92(4):e20201080. doi: 10.1590/0001-3765202020201080. eCollection 2020.
Cardiac glycosides have been found to have an anti-viral effect. This was noted in the past during various epidemics including MERS and SARS. It is due to their inhibitory effect on the Na, K-ATPase membrane pump. Furthermore, they exhibit anti-inflammatory properties. These preclinical observations may prove useful in further clinical utility of these well-known compounds in the current COVID-19 pandemic.