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乌干达 2 型糖尿病患者超重和肥胖的流行情况及相关因素:一项描述性回顾性研究。

Prevalence and factors associated with overweight and obesity among patients with type 2 diabetes mellitus in Uganda-a descriptive retrospective study.

机构信息

Non-Communicable Diseases, MRC/UVRI Uganda Research Unit On AIDS, Entebbe, Wakiso, Uganda

Non-Communicable Diseases, MRC/UVRI Uganda Research Unit On AIDS, Entebbe, Wakiso, Uganda.

出版信息

BMJ Open. 2020 Nov 4;10(11):e039258. doi: 10.1136/bmjopen-2020-039258.

Abstract

OBJECTIVES

To assess the prevalence and risk factors of overweight and obesity among type 2 diabetes mellitus (T2DM) patients in Uganda.

DESIGN

Retrospective chart review.

SETTING

This study was conducted in the outpatient's T2DM clinic in St. Francis Hospital-Nsambya, Uganda between March and May 2017.

PARTICIPANTS

Type 2 diabetes patients registered in the diabetes clinic between July 2003 and September 2016.

OUTCOME MEASURES

Overweight and obesity defined as body mass index (kg/m) of 25.0-29.9 and obesity as 30.0 or higher.

RESULTS

Of 1275 T2DM patients, the median age was 54 (IQR: 44-65) years, 770 (60.40%) were females, 887 (69.6%) had hypertension, 385 (28%) had controlled glycaemia, 349 (27%) were obese, while 455 (36%) were overweight. Overweight/obesity were lower among men (OR: 0.45, 95% CI: 0.340 to 0.593, p≤0.001) and among patients aged ≥65 years (OR: 0.52, 95% CI: 0.350 to 0.770, p=0.001); patients who rarely ate fruits and vegetables (OR: 0.66, 95% CI: 0.475 to 0.921, p=0.014) but higher among patients of middle (OR: 1.83, 95% CI: 1.320 to 2.550, p≤0.001) and upper (OR: 2.10, 95% CI: 1.450 to 2.990, p≤0.001) socioeconomic status; on dual therapy (OR: 2.17, 95% CI: 1.024 to 4.604, p=0.043); with peripheral neuropathy (OR: 1.40, 95% CI: 1.039 to 1.834, p=0.026) and hypertension (OR: 1.70, 95% CI: 1.264 to 2.293, p≤0.001).

CONCLUSIONS

Overweight and obesity are high among T2DM patients in this population and may contribute significantly to poor outcomes of T2DM. Therefore, strategies to address this problem are urgently needed.

摘要

目的

评估乌干达 2 型糖尿病(T2DM)患者超重和肥胖的流行率和风险因素。

设计

回顾性病历分析。

地点

本研究于 2017 年 3 月至 5 月期间在乌干达圣弗朗西斯医院-恩萨姆比亚的 T2DM 门诊进行。

参与者

2003 年 7 月至 2016 年 9 月期间在糖尿病诊所登记的 2 型糖尿病患者。

测量结果

超重和肥胖定义为身体质量指数(kg/m)为 25.0-29.9,肥胖定义为 30.0 或更高。

结果

在 1275 名 T2DM 患者中,中位年龄为 54(IQR:44-65)岁,770 名(60.40%)为女性,887 名(69.6%)患有高血压,385 名(28%)血糖控制良好,349 名(27%)肥胖,455 名(36%)超重。男性(OR:0.45,95%CI:0.340 至 0.593,p≤0.001)和 65 岁及以上患者(OR:0.52,95%CI:0.350 至 0.770,p=0.001)中超重/肥胖的发生率较低;很少吃水果和蔬菜的患者(OR:0.66,95%CI:0.475 至 0.921,p=0.014)但在中等(OR:1.83,95%CI:1.320 至 2.550,p≤0.001)和较高(OR:2.10,95%CI:1.450 至 2.990,p≤0.001)社会经济地位的患者中发生率较高;服用双重疗法(OR:2.17,95%CI:1.024 至 4.604,p=0.043);患有周围神经病变(OR:1.40,95%CI:1.039 至 1.834,p=0.026)和高血压(OR:1.70,95%CI:1.264 至 2.293,p≤0.001)的患者。

结论

该人群中 2 型糖尿病患者超重和肥胖的发生率较高,可能对 2 型糖尿病的不良结局有显著影响。因此,迫切需要制定解决这一问题的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edf0/7643505/13ef6f6677c5/bmjopen-2020-039258f01.jpg

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