Non-Communicable Diseases, MRC/UVRI Uganda Research Unit On AIDS, Entebbe, Wakiso, Uganda
Non-Communicable Diseases, MRC/UVRI Uganda Research Unit On AIDS, Entebbe, Wakiso, Uganda.
BMJ Open. 2020 Nov 4;10(11):e039258. doi: 10.1136/bmjopen-2020-039258.
To assess the prevalence and risk factors of overweight and obesity among type 2 diabetes mellitus (T2DM) patients in Uganda.
Retrospective chart review.
This study was conducted in the outpatient's T2DM clinic in St. Francis Hospital-Nsambya, Uganda between March and May 2017.
Type 2 diabetes patients registered in the diabetes clinic between July 2003 and September 2016.
Overweight and obesity defined as body mass index (kg/m) of 25.0-29.9 and obesity as 30.0 or higher.
Of 1275 T2DM patients, the median age was 54 (IQR: 44-65) years, 770 (60.40%) were females, 887 (69.6%) had hypertension, 385 (28%) had controlled glycaemia, 349 (27%) were obese, while 455 (36%) were overweight. Overweight/obesity were lower among men (OR: 0.45, 95% CI: 0.340 to 0.593, p≤0.001) and among patients aged ≥65 years (OR: 0.52, 95% CI: 0.350 to 0.770, p=0.001); patients who rarely ate fruits and vegetables (OR: 0.66, 95% CI: 0.475 to 0.921, p=0.014) but higher among patients of middle (OR: 1.83, 95% CI: 1.320 to 2.550, p≤0.001) and upper (OR: 2.10, 95% CI: 1.450 to 2.990, p≤0.001) socioeconomic status; on dual therapy (OR: 2.17, 95% CI: 1.024 to 4.604, p=0.043); with peripheral neuropathy (OR: 1.40, 95% CI: 1.039 to 1.834, p=0.026) and hypertension (OR: 1.70, 95% CI: 1.264 to 2.293, p≤0.001).
Overweight and obesity are high among T2DM patients in this population and may contribute significantly to poor outcomes of T2DM. Therefore, strategies to address this problem are urgently needed.
评估乌干达 2 型糖尿病(T2DM)患者超重和肥胖的流行率和风险因素。
回顾性病历分析。
本研究于 2017 年 3 月至 5 月期间在乌干达圣弗朗西斯医院-恩萨姆比亚的 T2DM 门诊进行。
2003 年 7 月至 2016 年 9 月期间在糖尿病诊所登记的 2 型糖尿病患者。
超重和肥胖定义为身体质量指数(kg/m)为 25.0-29.9,肥胖定义为 30.0 或更高。
在 1275 名 T2DM 患者中,中位年龄为 54(IQR:44-65)岁,770 名(60.40%)为女性,887 名(69.6%)患有高血压,385 名(28%)血糖控制良好,349 名(27%)肥胖,455 名(36%)超重。男性(OR:0.45,95%CI:0.340 至 0.593,p≤0.001)和 65 岁及以上患者(OR:0.52,95%CI:0.350 至 0.770,p=0.001)中超重/肥胖的发生率较低;很少吃水果和蔬菜的患者(OR:0.66,95%CI:0.475 至 0.921,p=0.014)但在中等(OR:1.83,95%CI:1.320 至 2.550,p≤0.001)和较高(OR:2.10,95%CI:1.450 至 2.990,p≤0.001)社会经济地位的患者中发生率较高;服用双重疗法(OR:2.17,95%CI:1.024 至 4.604,p=0.043);患有周围神经病变(OR:1.40,95%CI:1.039 至 1.834,p=0.026)和高血压(OR:1.70,95%CI:1.264 至 2.293,p≤0.001)的患者。
该人群中 2 型糖尿病患者超重和肥胖的发生率较高,可能对 2 型糖尿病的不良结局有显著影响。因此,迫切需要制定解决这一问题的策略。