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佩戴全口义齿的糖尿病患者与非糖尿病患者口干情况的比较评估

Comparative Evaluation of Xerostomia among Diabetic and Nondiabetic Subjects Wearing Complete Denture.

作者信息

Sundaram Manikandan, Manikandan Saranya, Satheesh Balakrishnan, Srinivasan Deenadayalan, Jayapal Dinakaran, Kumar Dhivya

机构信息

Department of Dental Surgery, Government Mohan Kumaramangalam Medical College and Hospital, Salem, Tamil Nadu, India.

Department of Oral Pathology, Vivekanandha Dental College for Women, Namakkal, Tamil Nadu, India.

出版信息

J Pharm Bioallied Sci. 2020 Aug;12(Suppl 1):S419-S422. doi: 10.4103/jpbs.JPBS_124_20. Epub 2020 Aug 28.

Abstract

BACKGROUND

Diabetes mellitus represents a group of metabolic diseases that are characterised by hyperglycaemia due to a total or relative lack of insulin secretion and insulin resistance or both. Diabetes mellitus patients present with a higher susceptibility to infections due to a deficiency in polymorphonuclear leukocytes, as a result of vascular alterations and neuropathies. An increased risk of infections has been observed in complete denture wearing subjects with xerostomia. The objective of this study was to compare diabetic and non-diabetic subjects wearing complete dentures regarding xerostomia of different age group.

MATERIALS AND METHODS

A cross-sectional study was conducted among 50 subjects, 25 with and 25 without a diagnosis of diabetes, were matched for gender, race, and age.

RESULTS

In this study we intended to compare diabetic and non-diabetic subjects wearing complete dentures regarding xerostomia and we found that xerostomia was more associated with diabetic denture wearer group in comparison with the non-diabetic denture wearers with a significant value of <0.05.

CONCLUSION

These results indicate that xerostomia should be diagnosed and effectively managed before any complete denture therapy is initiated in diabetic denture wearing patients to improve the quality of life.

摘要

背景

糖尿病是一组代谢性疾病,其特征是由于胰岛素分泌完全或相对不足以及胰岛素抵抗或两者兼而有之导致血糖升高。糖尿病患者由于血管改变和神经病变导致多形核白细胞缺乏,从而对感染的易感性更高。在佩戴全口义齿且患有口干症的受试者中,感染风险增加。本研究的目的是比较佩戴全口义齿的糖尿病患者和非糖尿病患者不同年龄组的口干情况。

材料与方法

对50名受试者进行了一项横断面研究,其中25名被诊断为糖尿病,25名未患糖尿病,两组在性别、种族和年龄上进行了匹配。

结果

在本研究中,我们旨在比较佩戴全口义齿的糖尿病患者和非糖尿病患者的口干情况,发现与非糖尿病义齿佩戴者相比,口干与糖尿病义齿佩戴者组的相关性更强,显著值<0.05。

结论

这些结果表明,在对佩戴义齿的糖尿病患者进行任何全口义齿治疗之前,应诊断并有效处理口干问题,以提高生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4971/7595564/af06b480ae20/JPBS-12-419-g001.jpg

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