Hasan Abdulkarim, Nafie Khalid, El-Sayed Samar, Nasr Mohamed, Abdulmohaymen Ayman, Baheeg Mohamed, Abbadi Osama
Department of Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Laboratory & Blood Bank Department, Prince Mishari Bin Saud Hospital, Baljurashi, Saudi Arabia.
Ann Med Surg (Lond). 2020 Oct 28;60:168-172. doi: 10.1016/j.amsu.2020.10.057. eCollection 2020 Dec.
This study identifies the incidence of appendiceal Enterobius vermicularis (E.v) infestation in all the patients undergoing appendectomy and evaluates the relationship between E. v infestation of the appendix and the acute appendicitis.
ology: All the routinely examined appendectomy specimens received in the pathology laboratory of a referral hospital over a three year period of time were reviewed for the existence of E. v. These cases were evaluated for clinico-laboratory characterization.
Out of 1150 appendectomies for clinical acute appendicitis picture, 31 (2.7%) cases revealed E. v infestation. The age ranged from 6 to 42 years old but more than 80% of the E. v infected cases were children. Twenty four cases (77.4%) did not show any other appendiceal pathology, six cases showed lymphoid hyperplasia and only one case showed concomitant histological acute inflammatory process.
E. v infestation is an incidental finding during histopathology examination of appendectomy specimens for patients with clinical diagnosis of acute appendicitis, however there is no relation between the existence of E. v and occurrence of acute appendicitis which is the main indication for appendectomy, so further studies are recommended to reach out earlier diagnosis to eliminate the unnecessary surgical intervention. Also surgeons should consider E. v as a differential diagnosis when removing a normal looking appendix to take the necessary precautions for minimizing any chance of contamination and sending all the normal looking appendectomy specimens for histopathology examination.
本研究确定了所有接受阑尾切除术的患者中阑尾蛲虫感染的发生率，并评估了阑尾蛲虫感染与急性阑尾炎之间的关系。
回顾了一家转诊医院病理实验室在三年时间内接收的所有常规检查的阑尾切除标本中是否存在蛲虫。对这些病例进行临床实验室特征评估。
在1150例因临床急性阑尾炎表现而进行的阑尾切除术中，31例（2.7%）发现有蛲虫感染。年龄范围为6至42岁，但超过80%的蛲虫感染病例为儿童。24例（77.4%）未显示任何其他阑尾病理改变，6例显示淋巴组织增生，仅1例显示伴有组织学上的急性炎症过程。
对于临床诊断为急性阑尾炎的患者，蛲虫感染是阑尾切除标本组织病理学检查中的一个偶然发现，然而蛲虫的存在与作为阑尾切除主要指征的急性阑尾炎的发生之间没有关系，因此建议进一步研究以实现早期诊断，消除不必要的手术干预。此外，外科医生在切除外观正常的阑尾时应将蛲虫感染作为鉴别诊断，采取必要的预防措施以尽量减少任何污染机会，并将所有外观正常的阑尾切除标本送去做组织病理学检查。
