一例抗核抗体阳性的成人斯蒂尔病

A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies.

作者信息

Lakshman Harini, Athwal Pal Satyajit Singh, Gondi Anitha, Dhillon Sandaljit, Towfiq Basim A

机构信息

Internal Medicine, Michigan State University at Hurley Medical Center, Flint, USA.

Internal Medicine, Saraswathi Institute of Medical Sciences, Hapur, IND.

出版信息

Cureus. 2020 Oct 1;12(10):e10761. doi: 10.7759/cureus.10761.

DOI:10.7759/cureus.10761

PMID:33150111

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7605080/

Abstract

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder involving multiple systems. It can present a wide range of symptoms like maculopapular rash, fever, and arthralgia, which may overlap with many other disorders, making it difficult to diagnose. Unknown etiology and no diagnostic tests further make it complex to establish the diagnosis of AOSD. We report the case of a 30-year-old female who presented with persistent rash, joint pain, and fever, along with positive antinuclear antibodies (ANA), diagnosed with this condition. The patient improved with corticosteroids and the plan is to start disease-modifying antirheumatic drugs (DMARDs) after tapering off steroids.

摘要

成人斯蒂尔病（AOSD）是一种累及多系统的罕见炎症性疾病。它可表现出多种症状，如斑丘疹、发热和关节痛，这些症状可能与许多其他疾病重叠，从而难以诊断。病因不明且缺乏诊断性检查进一步使得AOSD的诊断变得复杂。我们报告一例30岁女性病例，该患者出现持续性皮疹、关节疼痛和发热，同时抗核抗体（ANA）呈阳性，被诊断为此病。患者使用糖皮质激素后病情改善，计划在逐渐减少激素用量后开始使用改善病情抗风湿药（DMARDs）。