Schwarz-Eywill M, Heilig B, Bauer H, Breitbart A, Pezzutto A
Department of Internal Medicine, Med Poliklink V, University of Heidelberg, Germany.
Ann Rheum Dis. 1992 May;51(5):683-5. doi: 10.1136/ard.51.5.683.
Extremely high serum ferritin values (greater than 10,000 micrograms/l) were detected in two patients with adult Still's disease. The ferritin concentrations decreased to normal after adequate treatment. During a one year follow up ferritin concentration was helpful in monitoring disease activity and guiding decisions about treatment. Raised concentrations of soluble interleukin 2 receptors (sCD25) were also found. Detection of ferritin values above 3000 micrograms/l should lead to the consideration of Still's disease when there is an acute febrile illness without evidence for bacterial or viral infections, serum ferritin being suitable for monitoring treatment.
在两名成人斯蒂尔病患者中检测到血清铁蛋白值极高（大于10,000微克/升）。充分治疗后，铁蛋白浓度降至正常。在一年的随访中，铁蛋白浓度有助于监测疾病活动并指导治疗决策。还发现可溶性白细胞介素2受体（sCD25）浓度升高。当出现急性发热性疾病且无细菌或病毒感染证据时，检测到铁蛋白值高于3000微克/升应考虑斯蒂尔病，血清铁蛋白适用于监测治疗。
