评估血清铁蛋白作为成人斯蒂尔病活动度标志物的作用。
Evaluation of serum ferritin as a marker for adult Still's disease activity.
作者信息
Schwarz-Eywill M, Heilig B, Bauer H, Breitbart A, Pezzutto A
机构信息
Department of Internal Medicine, Med Poliklink V, University of Heidelberg, Germany.
出版信息
Ann Rheum Dis. 1992 May;51(5):683-5. doi: 10.1136/ard.51.5.683.
Abstract
Extremely high serum ferritin values (greater than 10,000 micrograms/l) were detected in two patients with adult Still's disease. The ferritin concentrations decreased to normal after adequate treatment. During a one year follow up ferritin concentration was helpful in monitoring disease activity and guiding decisions about treatment. Raised concentrations of soluble interleukin 2 receptors (sCD25) were also found. Detection of ferritin values above 3000 micrograms/l should lead to the consideration of Still's disease when there is an acute febrile illness without evidence for bacterial or viral infections, serum ferritin being suitable for monitoring treatment.
摘要
在两名成人斯蒂尔病患者中检测到血清铁蛋白值极高（大于10,000微克/升）。充分治疗后，铁蛋白浓度降至正常。在一年的随访中，铁蛋白浓度有助于监测疾病活动并指导治疗决策。还发现可溶性白细胞介素2受体（sCD25）浓度升高。当出现急性发热性疾病且无细菌或病毒感染证据时，检测到铁蛋白值高于3000微克/升应考虑斯蒂尔病，血清铁蛋白适用于监测治疗。
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