Freiman I, Hartman E, Kassel H, Robins-Browne R M, Schoub B D, Koornhof H J, Lecatsas G, Prozesky O W
S Afr Med J. 1977 Aug 6;52(7):261-5.
A survey was carried out to determine the aetiological agents responsible for acute gastro-enteritis in Black infants. Bacteriological examination of 191 patients and 178 age-matched controls showed that salmonellae and shigellae together accounted for only 15% of cases and were harboured by almost 7% of controls. Seropositive 'enteropathogenic' Escherichia coli was an important cause of diarrhoea, especially in the summer months. Enterotoxin-producing E. coli was not a significant cause of gastro-enteritis in this study. This study suggests that routine serotyping of E. coli from infantile gastro-enteritis should be continued until the relationship of serotype and enterotoxigenicity with enteropathogenicity has been established. Rotaviruses were detected by electron microscopy in 14,4% of children. The clinical features associated with the different infectious agents are described.
开展了一项调查,以确定导致黑人婴儿急性胃肠炎的病原体。对191名患者和178名年龄匹配的对照者进行细菌学检查发现,沙门氏菌和志贺氏菌合起来仅占病例的15%,而近7%的对照者携带这些病菌。血清反应呈阳性的“肠致病性”大肠杆菌是腹泻的一个重要病因,尤其是在夏季。在本研究中,产肠毒素大肠杆菌并非胃肠炎的重要病因。该研究表明,在血清型和产肠毒素能力与肠致病性的关系确立之前,应继续对婴儿胃肠炎患者的大肠杆菌进行常规血清分型。通过电子显微镜在14.4%的儿童中检测到了轮状病毒。文中描述了与不同感染原相关的临床特征。