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产肠毒素性大肠杆菌O6.H16引起的婴儿肠炎暴发

Outbreak of infantile enteritis caused by enterotoxigenic Escherichia coli O6.H16.

作者信息

Rowe B, Gross R J, Scotland S M, Wright A E, Shillom G N, Hunter N J

出版信息

J Clin Pathol. 1978 Mar;31(3):217-9. doi: 10.1136/jcp.31.3.217.

Abstract

Ten out of 18 babies at risk developed enteritis in an outbreak in a special-care baby unit. Salmonella, Shigella, and Escherichia coli belonging to the traditional infantile enteropathogenic serogroups were not found in faeces from the babies and the staff, and no virus particles were found by electron microscopy. Detailed serotyping of E. coli showed that five of the 10 babies with diarrhoea and one of the eight without diarrhoea were excreting E. coli O6.H16. All six isolates of this serotype produced both heat-labile and heat-stable enterotoxin. Enterotoxigenic strains of E. coli O6.H16 have caused outbreaks of enteritis in adults in the USA and Japan.

摘要

在一个特殊护理婴儿病房爆发的疫情中,18名有风险的婴儿中有10名患上了肠炎。在婴儿和工作人员的粪便中未发现属于传统婴儿肠道致病血清群的沙门氏菌、志贺氏菌和大肠杆菌,并且通过电子显微镜未发现病毒颗粒。大肠杆菌的详细血清分型显示,10名腹泻婴儿中的5名和8名未腹泻婴儿中的1名正在排出大肠杆菌O6.H16。该血清型的所有6株分离菌均产生不耐热和耐热肠毒素。在美国和日本,大肠杆菌O6.H16的产肠毒素菌株已导致成人肠炎爆发。

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本文引用的文献

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Infantile diarrhea produced by heat-stable enterotoxigenic Escherichia coli.
N Engl J Med. 1976 Oct 14;295(16):849-53. doi: 10.1056/NEJM197610142951601.

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