Department of Critical Care Medicine, Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated to Soochow University), Suzhou, Jiangsu, China.
Department of Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
PLoS One. 2020 Nov 5;15(11):e0241540. doi: 10.1371/journal.pone.0241540. eCollection 2020.
Coronavirus disease 2019 (COVID-19) has spread to the world. Whether there is an association between lifestyle behaviors and the acquisition of COVID-19 remains unclear.
In this case-control study, we recruited 105 patients with SARS-CoV-2 infection as a case group from the Wuhan Tongji Hospital (Wuhan, China). For each case two control subjects were recruited. Participants were randomly selected from communities in Wuhan and matched for sex, age (± 2yrs), and pre-existing comorbidities (hypertension and diabetes).
A total of 105 patients diagnosed with COVID-19 and 210 controls were included. Compared with control group, the case group had higher proportions of lack of sleep (30.5% vs. 14.8%, P = 0.001) and increased physical activities (56.2% vs. 32.9%, P < 0.001). And patients in the case group were more likely to have alopecia (28.6% vs. 10.0%, P < 0.001) than people from the control group. Overall, we found that lack of sleep [adjusted odds ratio (OR) 1.56, 95% confidence interval (CI) 1.03-2.39)], physical activities (≥ 5 times a week) (adjusted OR 2.05, 95%CI 1.39-3.02) and alopecia (adjusted OR 1.73, 95%CI 1.13-2.66) were independent risk factors for COVID-19 infection. Conversely, low-dose alcohol intake (<100g alcohol per week), hand hygiene, and fruits intake (daily) were significantly associated with a decrease in morbidity.
Individual lifestyle behaviors and health status can affect the occurrence of COVID-19.
2019 年冠状病毒病（COVID-19）已在全球范围内传播。生活方式行为与 COVID-19 的发生之间是否存在关联尚不清楚。
在这项病例对照研究中，我们从中国武汉同济医院招募了 105 名 SARS-CoV-2 感染患者作为病例组。对于每个病例，我们招募了 2 名对照。参与者是从武汉社区中随机选择的，按性别、年龄（±2 岁）和既往合并症（高血压和糖尿病）进行匹配。
共纳入 105 例确诊 COVID-19 的患者和 210 名对照。与对照组相比，病例组睡眠不足的比例更高（30.5%比 14.8%，P=0.001），体力活动增加（56.2%比 32.9%，P<0.001）。病例组脱发的患者（28.6%比 10.0%，P<0.001）比对照组更常见。总的来说，我们发现睡眠不足（调整后的优势比[OR]1.56，95%置信区间[CI]1.03-2.39））、每周体力活动≥5 次（调整后的 OR 2.05，95%CI 1.39-3.02）和脱发（调整后的 OR 1.73，95%CI 1.13-2.66）是 COVID-19 感染的独立危险因素。相反，低剂量饮酒（<100g 酒精/周）、手部卫生和水果摄入（每日）与发病率降低显著相关。
个体生活方式行为和健康状况可能会影响 COVID-19 的发生。
