Department of Epidemiology, Brown University School of Public Health, Box G-S121-2, 121 South Main Street, Providence, RI 02912, USA.
Department of Epidemiology, Brown University School of Public Health, Box G-S121-2, 121 South Main Street, Providence, RI 02912, USA. Electronic address: https://twitter.com/JosephMBraun1.
Endocrinol Metab Clin North Am. 2020 Dec;49(4):759-770. doi: 10.1016/j.ecl.2020.08.004. Epub 2020 Oct 14.
Phthalates, a class of endocrine-disrupting chemicals, are used widely in many consumer products, and exposure can interfere with a range of hormonal functions during early life. These disruptions may alter development during late childhood and adolescence. This article discusses the potential effects of phthalate exposure on adiposity, puberty, and neurodevelopment during late childhood and adolescence. It also highlights studies of behavioral interventions to reduce phthalate exposures and the roles of health care professionals and policy makers in preventing phthalate exposure.
邻苯二甲酸酯类是一类内分泌干扰化学物质,广泛应用于许多消费产品中,其暴露可能会干扰生命早期的一系列激素功能。这些干扰可能会改变儿童晚期和青春期的发育过程。本文讨论了邻苯二甲酸酯暴露对儿童晚期和青春期肥胖、青春期和神经发育的潜在影响。还强调了减少邻苯二甲酸酯暴露的行为干预研究,以及卫生保健专业人员和政策制定者在预防邻苯二甲酸酯暴露方面的作用。