Sarmiento-Hernández Isabel, Pérez-Marín María de Los Ángeles, Nunez-Nagy Susana, Pecos-Martín Daniel, Gallego-Izquierdo Tomás, Sosa-Reina M Dolores
Technology University of Tulancingo, Tulancingo, Hidalgo, México.
Private Physiotherapy Clinic, Puebla, México.
Pain Med. 2020 Dec 25;21(12):3499-3511. doi: 10.1093/pm/pnaa321.
To attain a synthesis of the evidence on the effectiveness of invasive techniques in patients with fibromyalgia, through systematic review and meta-analysis and by assessing the methodological quality of the studies considered.
A systematic review and meta-analysis were carried out as defined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The bibliographic research was carried out in the PEDro, Cochrane, PubMed, Science Direct, Web of Science, Google Academics, Dialnet, and Scielo databases from September through December of 2018.
Results show that invasive techniques produce a significant decrease in the pain, the impact of fibromyalgia and in the pain pressure threshold (standardized mean difference [95% confidence interval]: -0.94 [-1.44, -0.44], P of global effect= 0.0002; -0.99 [-1.69, -0.29], P of global effect= 0.006; and 0.31 [0.02, 0.61], P of global effect = 0.04, respectively). Lastly, a significant increase was observed in the quality-of-life variable after intervention (0.84 [0.30, 1.38], P of global effect = 0.002).
Invasive techniques are considered effective for pain relief, as well as for producing a short-term increase in the pain pressure threshold, an improvement in quality of life, and a decrease in the impact of fibromyalgia.
通过系统评价和荟萃分析，并评估所纳入研究的方法学质量，综合有关侵入性技术治疗纤维肌痛患者有效性的证据。
按照系统评价和荟萃分析的首选报告项目（PRISMA）声明中所定义的进行系统评价和荟萃分析。于2018年9月至12月在PEDro、Cochrane、PubMed、科学Direct、科学网、谷歌学术、Dialnet和Scielo数据库中进行文献检索。
结果显示，侵入性技术可使疼痛、纤维肌痛的影响以及疼痛压力阈值显著降低（标准化均数差[95%置信区间]：分别为-0.94[-1.44, -0.44]，总体效应P = 0.0002；-0.99[-1.69, -0.29]，总体效应P = 0.006；以及0.31[0.02, 0.61]，总体效应P = 0.04）。最后，干预后生活质量变量显著提高（0.84[0.30, 1.38]，总体效应P = 0.002）。
侵入性技术被认为对缓解疼痛有效，还能使疼痛压力阈值短期内提高、生活质量改善以及纤维肌痛的影响减轻。
