Zhang Yangyang, Ouyang Zhihua, Wang Wenjun
Department of Spinal Surgery, the First Affiliated Hospital of University of South China, Hengyang, Hunan, People's Republic of China.
Medicine (Baltimore). 2020 Nov 6;99(45):e22744. doi: 10.1097/MD.0000000000022744.
Anterior cervical discectomy and fusion (ACDF) is the gold standard treatment for this cervical radiculopathy. Posterior endoscopic cervical foraminotomy (PECF), an effective alternative to ACDF, is becoming widely used by an increasing number of surgeons. However, comparisons of the clinical outcomes of ACDF and PECF remain poorly explored. The purpose of this study was to evaluate and compare visual analog scale (VAS)-arm scores, VAS-neck scores, neck disability index (NDI) scores, reoperation, and complications in PECF and ACDF.
We comprehensively searched electronic databases or platforms, including PubMed, Web of Science, EMBASE, and the Cochrane Controlled Trial Center, using the PRISMA guidelines. The required information, including VAS-arm scores, VAS-neck scores, NDI scores, reoperation, and complications, was extracted from qualified studies and independently tested and compared by 2 researchers. The methodological index for nonrandomized studies was used to evaluate study quality.
Nine studies consisting of 230 males and 256 females were included. The mean age of the included patients was 49.6 years, and the mean follow-up time was 20.6 months. The VAS-arm scores were significantly higher, and VAS-neck scores and NDI scores of PECF showed greater improvement trends for PECF than ACDF. The complication proportion of patients with PECF was lower, while the proportion of reoperation was similar between PECF and ACDF. ACDF was the most common revision surgery. The most common complication of PECF was transient paresthesia.
Compared with ACDF, PECF is safe and effective in patients with unilateral cervical radiculopathy without myelopathy, and PECF does not increase the probability of reoperation and complications.
颈椎前路椎间盘切除融合术(ACDF)是治疗这种神经根型颈椎病的金标准。后路内镜下颈椎椎间孔切开术(PECF)作为ACDF的一种有效替代方法,正被越来越多的外科医生广泛应用。然而,ACDF和PECF临床疗效的比较仍缺乏深入研究。本研究的目的是评估和比较PECF与ACDF的视觉模拟量表(VAS)上肢评分、VAS颈部评分、颈部功能障碍指数(NDI)评分、再次手术情况及并发症。
我们按照PRISMA指南全面检索了电子数据库或平台,包括PubMed、科学网、EMBASE和Cochrane对照试验中心。从符合条件的研究中提取所需信息,包括VAS上肢评分、VAS颈部评分、NDI评分、再次手术情况及并发症,并由两名研究人员独立进行测试和比较。采用非随机研究的方法学指标评估研究质量。
纳入9项研究,共230例男性和256例女性。纳入患者的平均年龄为49.6岁,平均随访时间为20.6个月。PECF的VAS上肢评分显著更高,且PECF的VAS颈部评分和NDI评分改善趋势大于ACDF。PECF患者的并发症比例较低,而PECF与ACDF的再次手术比例相似。ACDF是最常见的翻修手术。PECF最常见的并发症是短暂性感觉异常。
与ACDF相比,PECF对于无脊髓病的单侧神经根型颈椎病患者安全有效,且PECF不会增加再次手术和并发症的发生率。